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ChemicalBook > Product Catalogue >API >Diagnostic agents >Organ Function Test agent >METYRAPONE

METYRAPONE

METYRAPONE Structure
  • ₹2305.73 - ₹26477.95
  • Product name: METYRAPONE
  • CAS: 54-36-4
  • MF: C14H14N2O
  • MW: 226.27
  • EINECS:200-206-2
  • MDL Number:MFCD00006397
  • Synonyms:Metapirone;Metapyrone;Methapyrapone;Methbipyranone;Methopirapone;Methopyrapone;Methopyrinine;Methopyrone
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 250MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product number856525
  • Product description2-Methyl-1,2-di-3-pyridyl-1-propanone 96%
  • Packaging250MG
  • Price₹2305.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM2696
  • Product descriptionMetyrapone ≥98% (HPLC), solid
  • Packaging10MG
  • Price₹7339.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number856525
  • Product description2-Methyl-1,2-di-3-pyridyl-1-propanone 96%
  • Packaging1G
  • Price₹8237.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM2696
  • Product descriptionMetyrapone ≥98% (HPLC), solid
  • Packaging50MG
  • Price₹26477.95
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 856525 2-Methyl-1,2-di-3-pyridyl-1-propanone 96% 250MG ₹2305.73 2022-06-14 Buy
Sigma-Aldrich(India) M2696 Metyrapone ≥98% (HPLC), solid 10MG ₹7339.35 2022-06-14 Buy
Sigma-Aldrich(India) 856525 2-Methyl-1,2-di-3-pyridyl-1-propanone 96% 1G ₹8237.83 2022-06-14 Buy
Sigma-Aldrich(India) M2696 Metyrapone ≥98% (HPLC), solid 50MG ₹26477.95 2022-06-14 Buy

Properties

Melting point :52-55 °C(lit.)
Boiling point :367.89°C (rough estimate)
Density :1.0852 (rough estimate)
refractive index :1.6419 (estimate)
Flash point :>230 °F
storage temp. :Inert atmosphere,Room Temperature
solubility :H2O: soluble (sparingly)
form :solid
pka :4.61±0.10(Predicted)
color :White
Merck :13,6181
BRN :163023
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
EPA Substance Registry System :Metyrapone (54-36-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Metyrapone blocks cortisol synthesis by inhibiting steroid 11β-hydroxylase in adrenal cortex (IC50 = 7.8 μM). Metyrapone binds with high affinity to cytochrome P(CYP)450 in hepatic microsomes and induces rat hepatic CYP1A1 and CYP3A gene expression. It is used to assess adrenal insufficiency, to address hypercortisolism characteristic of Cushing’s syndrome, and may be of clinical value in the treatment of depression and in reducing brain damage resulting from hypoxia-ischemia.

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Suppliers and manufacturers

career henan chemical co
METYRAPONE
₹7.00 /1kg
METYRAPONE CAS: 54-36-4
TargetMol Chemicals Inc.
Metyrapone
₹34.00 /50mg
Metyrapone CAS:54-36-4
CLEARSYNTH LABS LTD. A.J Chemicals Pharmaffiliates Analytics and Synthetics P. Ltd
SHANDONG ZHI SHANG CHEMICAL CO.LTD
Hefei TNJ Chemical Industry Co.,Ltd.
Shaanxi Dideu Medichem Co. Ltd
AFINE CHEMICALS LIMITED
Zhejiang J&C Biological Technology Co.,Limited