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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Adrenal corticosteroids >Methylprednisolone

Methylprednisolone

Methylprednisolone Structure
  • ₹9807.45 - ₹97977.08
  • Product name: Methylprednisolone
  • CAS: 83-43-2
  • MF: C22H30O5
  • MW: 374.47
  • EINECS:201-476-4
  • MDL Number:MFCD00010591
  • Synonyms:20-dione,11-beta,17,21-trihydroxy-6-alpha-methyl-pregna-4-diene-3 ;20-dione,11beta,17,21-trihydroxy-6alpha-methyl-pregna-4-diene-3 ;20-dione,6-alpha-methyl-11-beta-17,21-trihydroxy-pregna-4-diene-3 ;6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione ;artisone-wyeth ;Besonia;delta(1)-6alpha-methylhydrocortisone ;Suprametil
Price5 Properties Safety Information Description
5 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • 250MG
  • 500MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberM0639
  • Product description6α-Methylprednisolone ≥98%
  • Packaging1G
  • Price₹97977.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM0639
  • Product description6α-Methylprednisolone ≥98%
  • Packaging250MG
  • Price₹36491.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number46436
  • Product description6α-Methylprednisolone VETRANAL?, analytical standard
  • Packaging100MG
  • Price₹21227.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM0639
  • Product description6α-Methylprednisolone ≥98%
  • Packaging100MG
  • Price₹18824.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1717
  • Product descriptionMethylprednisolone Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹9807.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) M0639 6α-Methylprednisolone ≥98% 1G ₹97977.08 2022-06-14 Buy
Sigma-Aldrich(India) M0639 6α-Methylprednisolone ≥98% 250MG ₹36491.08 2022-06-14 Buy
Sigma-Aldrich(India) 46436 6α-Methylprednisolone VETRANAL?, analytical standard 100MG ₹21227.83 2022-06-14 Buy
Sigma-Aldrich(India) M0639 6α-Methylprednisolone ≥98% 100MG ₹18824.68 2022-06-14 Buy
Sigma-Aldrich(India) PHR1717 Methylprednisolone Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹9807.45 2022-06-14 Buy

Properties

Melting point :228-237°C (dec.)
alpha :D20 +83° (dioxane)
Boiling point :423.47°C (rough estimate)
Density :1.0868 (rough estimate)
refractive index :82 ° (C=1, Dioxane)
storage temp. :0-6°C
solubility :chloroform/methanol (9:1): 50 mg/mL, clear, faintly yellow
form :Solid
pka :12.46±0.70(Predicted)
color :White to Off-White
Water Solubility :0.12g/L(25 ºC)
Merck :14,6111
BRN :2340300
BCS Class :2 or 4?
InChIKey :VHRSUDSXCMQTMA-PJHHCJLFSA-N
CAS DataBase Reference :83-43-2(CAS DataBase Reference)
NIST Chemistry Reference :1,4-Pregnadiene-3,20-dione, 11beta,17alpha,21-trihydroxy-6alpha-methyl-(83-43-2)
EPA Substance Registry System :Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6.alpha.,11.beta.)- (83-43-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Prednisolone is the active metabolite of the synthetic corticosteroid prednisone, which is used to suppress inflammation and autoimmunity, as well as in other conditions. Methylprednisolone is a 6α-methyl derivative of prednisolone, a variation which reduces its binding to corticosteroid-binding globulin and increases penetration into target tissues. It alters gene expression, like prednisolone, through both the glucocorticoid and mineralocorticoid receptors.

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