Methylprednisolone hemisuccinate
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- ₹0
- Product name: Methylprednisolone hemisuccinate
- CAS: 2921-57-5
- MF: C26H34O8
- MW: 474.54
- EINECS:220-863-9
- MDL Number:MFCD00271782
- Synonyms:6-alpha-Methyl Isomer of Methylhydrocortisone 21-Hydrogen Succinate;11β,17,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-succinate;6a- methyl prednisolone acetate half Kohaku;4-diene-3,20-dione,11-beta,17,21-trihydroxy-6-alpha-methyl-pregna-21-(hy ;4-diene-3,20-dione,11-beta,17,21-trihydroxy-6-alpha-methyl-pregna-21-suc ;6-methylprednisolonehemisuccinate ;Methylprednisolone sucsinate;Methylprednisolone Hemisuccinate (200 mg)
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Properties
Melting point :>230°C (dec.)
Boiling point :689.6±55.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Practically insoluble in water, slightly soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali hydroxides.
pka :4.29±0.17(Predicted)
form :Solid
color :White to Off-White
LogP :2.69
CAS DataBase Reference :2921-57-5(CAS DataBase Reference)
Boiling point :689.6±55.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Practically insoluble in water, slightly soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali hydroxides.
pka :4.29±0.17(Predicted)
form :Solid
color :White to Off-White
LogP :2.69
CAS DataBase Reference :2921-57-5(CAS DataBase Reference)
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
Methylprednisolone is a synthetic glucocorticoid that has anti-inflammatory and immunosuppressant effects through the glucocorticoid receptor. The methyl group reduces specific binding to corticosteroid-binding globulin, which may allow better tissue penetration, compared to that of prednisolone. 6α-Methylprednisolone 21-hemisuccinate is a prodrug for methylprednisolone. This compound has superior water solubility compared to the active glucocorticoid.Related product price
- Prednisolone-21-acetate
₹6419.23-22245.38 - Methylprednisolone acetate
₹9883.23 - 6alpha-Methylprednisolone sodium succinate
₹7826.48-105013.33