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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Adrenal corticosteroids >Prednisone

Prednisone

Prednisone Structure
  • ₹0
  • Product name: Prednisone
  • CAS: 53-03-2
  • MF: C21H26O5
  • MW: 358.43
  • EINECS:200-160-3
  • MDL Number:MFCD00003608
  • Synonyms:1,2-Dehydrocortisone;1,4-pregnadiene-16-alpha,21-diol-3,11,20-trione ;11,20-trione,17,21-dihydroxy-pregna-4-diene-3 ;11,20-trione,17,21-hydroxy-pregna-4-diene-3 ;Ancortone;Colisone;Cortancyl;Cortidelt
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :236-238 °C(lit.)
alpha :169 º (c=0.5, dioxane)
Boiling point :410.86°C (rough estimate)
Density :1.1121 (rough estimate)
refractive index :170 ° (C=0.5, Dioxane)
Flash point :>200℃
storage temp. :2-8°C
solubility :Practically insoluble in water, slightly soluble in ethanol (96 per cent) and in methylene chloride. It shows polymorphism (5.9).
pka :12.36±0.60(Predicted)
form :Solid
color :White to Off-White
Water Solubility :115mg/L(25 ºC)
Merck :7722
BRN :2065301
BCS Class :1?
Stability :Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference :53-03-2(CAS DataBase Reference)
IARC :3 (Vol. 26, Sup 7) 1987
NIST Chemistry Reference :Prednisone(53-03-2)
EPA Substance Registry System :Prednisone (53-03-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.

Description

Prednisone reduces mucosal TNF-a production, intestinal permeability and levels of NF-κB expression.

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