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Mal-PEG4-NHS ester

Mal-PEG4-NHS ester Structure
  • ₹0
  • Product name: Mal-PEG4-NHS ester
  • CAS: 1325208-25-0
  • MF: C19H26N2O10
  • MW: 442.42
  • EINECS:
  • MDL Number:MFCD20230464
  • Synonyms:Mal-PEG4-NHS ester;4,7,10,13-Tetraoxapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester;2,5-dioxopyrrolidin-1-yl1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12-tetraoxapentadecan-15-oate;MAL-PEG4-Osu;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate;Mal-PEG4-CH2CH2COONHS
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :580.5±60.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Soluble in DCM
pka :-2.34±0.20(Predicted)
form :Solid-Liquid Mixture
color :Off-white to yellow
InChI :InChI=1S/C19H26N2O10/c22-15-1-2-16(23)20(15)6-8-28-10-12-30-14-13-29-11-9-27-7-5-19(26)31-21-17(24)3-4-18(21)25/h1-2H,3-14H2
InChIKey :TUPOSLKVPPFQGR-UHFFFAOYSA-N
SMILES :C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCN1C(=O)C=CC1=O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Mal-PEG4-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

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