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ChemicalBook > Product Catalogue >API >Nervous system drugs >Cholinergic drugs >Mestinon

Mestinon

Mestinon Structure
  • ₹11800 - ₹41254.08
  • Product name: Mestinon
  • CAS: 101-26-8
  • MF: C9H13BrN2O2
  • MW: 261.12
  • EINECS:202-929-9
  • MDL Number:MFCD00079283
  • Synonyms:mestinonbromide ;mestinonebromide ;pyridinium,3-hydroxy-1-methyl-,bromide,dimethylcarbamate(ester) ;pyridinium,3-hydroxyl-1-methyl-,bromide,dimethylcarbamate ;regonal ;ro1-5130 ;1-methyl-3-hydroxypyridiniumbromidedimethylcarbamate ;PYRIDOSTIGMINEBROMIDE,USP
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberP1339
  • Product descriptionPyridostigmine Bromide
  • Packaging5G
  • Price₹11800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1339
  • Product descriptionPyridostigmine Bromide
  • Packaging25G
  • Price₹19100
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP9797
  • Product descriptionPyridostigmine bromide
  • Packaging1G
  • Price₹12719.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR3120
  • Product descriptionPyridostigmine Bromide pharmaceutical secondary standard, certified reference material
  • Packaging500MG
  • Price₹16724.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP9797
  • Product descriptionPyridostigmine bromide
  • Packaging5G
  • Price₹41254.08
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P1339 Pyridostigmine Bromide 5G ₹11800 2022-05-26 Buy
TCI Chemicals (India) P1339 Pyridostigmine Bromide 25G ₹19100 2022-05-26 Buy
Sigma-Aldrich(India) P9797 Pyridostigmine bromide 1G ₹12719.38 2022-06-14 Buy
Sigma-Aldrich(India) PHR3120 Pyridostigmine Bromide pharmaceutical secondary standard, certified reference material 500MG ₹16724.63 2022-06-14 Buy
Sigma-Aldrich(India) P9797 Pyridostigmine bromide 5G ₹41254.08 2022-06-14 Buy

Properties

Melting point :154 °C
storage temp. :2-8°C
solubility :Very soluble in water and in ethanol (96 per cent).
form :Solid
color :White to Almost white
Merck :14,7977
BCS Class :3
InChIKey :VNYBTNPBYXSMOO-UHFFFAOYSA-M
CAS DataBase Reference :101-26-8(CAS DataBase Reference)
EPA Substance Registry System :Pyridinium, 3-[[(dimethylamino)carbonyl]oxy]-1-methyl-, bromide (1:1) (101-26-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Pyridostigmine is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 0.35 and 1 μM, respectively, for the human enzymes). Pyridostigmine (10 μM) reduces decreases in AChE activity induced by the organophosphate pesticides diisopropyl fluorophosphate, chlorpyrifos-oxon, diazinon-oxon, paraoxon, and malaoxon in isolated bovine red blood cells. It also reduces soman-induced membrane depolarization and decreases in AChE activity in isolated human muscle bundles in a concentration-dependent manner. Pyridostigmine (3 mg/kg per day for four weeks) prevents tachycardia and increases in sympathetic tone in mice following myocardial infarction induced by left coronary artery ligation. Formulations containing pyridostigmine have been used in the treatment of myasthenia gravis and as neuromuscular protective agents against organophosphate poisoning.

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Suppliers and manufacturers

PANCHSHEEL ORGANICS LTD Surajlok Chemicals Pvt Ltd (Neon Laboratories Ltd) Sami Sabinsa Group Limited (formerly Sami Labs Limited) Global Calcium Pvt Ltd Ruskin Chemipharm Ramkishore Chemical Company Pvt. Ltd. Meruvax Pharma (South Asia) Merit International MAITHRI LABORATORIES PRIVATE LTD CLEARSYNTH LABS LTD.