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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Metformin hydrochloride

Metformin hydrochloride

Metformin hydrochloride Structure
  • ₹5300 - ₹19700
  • Product name: Metformin hydrochloride
  • CAS: 1115-70-4
  • MF: C4H12ClN5
  • MW: 165.62
  • EINECS:214-230-6
  • MDL Number:MFCD00012582
  • Synonyms:1,1-dimethyl-biguanidhydrochloride ;diabefagos ;diformin ;dimethylbiguanidehydrochloride ;Dimethyldiguanidinehydrochloride ;DIABETOSAN;DIABEX;N,N-DIMETHYLIMIDODICARBONIMIDIC DIAMIDE HYDROCHLORIDE
Price6 Properties Safety Information Description
6 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 1ML
  • 5G
  • 25G
  • 100G
  • ManufacturerTCI Chemicals (India)
  • Product numberM2009
  • Product descriptionMetformin Hydrochloride
  • Packaging25G
  • Price₹5300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM2009
  • Product descriptionMetformin Hydrochloride
  • Packaging100G
  • Price₹19700
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1084
  • Product descriptionMetformin hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹9991.48
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD150959
  • Product description1,1-Dimethylbiguanide hydrochloride 97%
  • Packaging5G
  • Price₹11853.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number317240
  • Product descriptionMetformin - CAS 1115-70-4 - Calbiochem An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia.
  • Packaging5G
  • Price₹12630.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM-072
  • Product descriptionMetformin hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹13167
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M2009 Metformin Hydrochloride 25G ₹5300 2022-05-26 Buy
TCI Chemicals (India) M2009 Metformin Hydrochloride 100G ₹19700 2022-05-26 Buy
Sigma-Aldrich(India) PHR1084 Metformin hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹9991.48 2022-06-14 Buy
Sigma-Aldrich(India) D150959 1,1-Dimethylbiguanide hydrochloride 97% 5G ₹11853.38 2022-06-14 Buy
Sigma-Aldrich(India) 317240 Metformin - CAS 1115-70-4 - Calbiochem An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia. 5G ₹12630.01 2022-06-14 Buy
Sigma-Aldrich(India) M-072 Metformin hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹13167 2022-06-14 Buy

Properties

Melting point :223-226 °C(lit.)
Density :1.36[at 20℃]
vapor pressure :0.001Pa at 25℃
Flash point :9℃
storage temp. :2-8°C
solubility :Freely soluble in water, slightly soluble in alcohol, practically insoluble in acetone and in methylene chloride
pka :12.4[at 20 ℃]
form :Powder
color :White
Water Solubility :Soluble in water (50 mg/ml), ethanol, and DMSO (50 mM).
λmax :233nm(H2O)(lit.)
Merck :14,5938
BCS Class :3
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.
InChIKey :OETHQSJEHLVLGH-UHFFFAOYSA-N
LogP :-3.5 at 20℃
CAS DataBase Reference :1115-70-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Metformin is an orally administered biguanide derivative used to lower blood glucose concentrations in patients with non-insulin-dependent diabetes mellitus. It improves insulin sensitivity and decreases insulin resistance by inhibiting Complex 1 of the mitochondrial respiratory chain and inducing AMP-activated protein kinase-dependent signaling. At 50-400 mg/kg body weight, metformin can stimulate glucose uptake in skeletal muscle and suppress hepatic gluconeogenesis in B6-Lepob/ob mice. Metformin has also been shown to improve fatty liver disease by reversing hepatic steatosis in ob/ob mice, restoring ovarian function in polycystic ovary syndrome, and directly inhibiting tumor growth in cancer cell lines.

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Suppliers and manufacturers

ANWITA APIS GRINDLAYS PHARMACEUTICALS PRIVATE LIMITED Frolic Pharmachem GLP Pharma Standards Vivimed Labs Ltd Ipca Laboratories Ltd Smruthi Organics Limited Soujanya Life Sciences Harman Finochem Ltd Abhilash Chemicals And Pharmaceuticals Pvt. Ltd.