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Milbemycin D

Milbemycin D Structure
  • ₹0
  • Product name: Milbemycin D
  • CAS: 77855-81-3
  • MF: C33H48O7
  • MW: 556.73
  • EINECS:
  • MDL Number:
  • Synonyms:Milbemycin D;(6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-(1-methylethyl)milbemycin B;Antibiotic B-41D;B-41D;MilbeMycin MIL;(6r,25)-5-o-demethyl-28-deoxy-6,28-epoxy-25-(1-methylethyl)milbemycin b;Milbemycin EP Impurity C;Milbemycin Impurity 3(Milbemycin EP Impurity C)
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Properties

Melting point :186-188°
alpha :D27 +107° (c = 0.25 in acetone)
Boiling point :460.61°C (rough estimate)
Density :1.0367 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly)
form :Solid
pka :12.46±0.70(Predicted)
color :White to Off-White
Stability :Hygroscopic

Safety Information

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Description

Milbemycin D is a minor member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. It potentiates glutamate and GABA-gated chloride channel opening (EC50 = 89 nM) and has been used as a nematocide and insecticide.

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