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N-Arachidonyl maleimide

N-Arachidonyl maleimide Structure
  • ₹0
  • Product name: N-Arachidonyl maleimide
  • CAS: 876305-42-9
  • MF: C24H35NO2
  • MW: 369.54
  • EINECS:
  • MDL Number:MFCD11521506
  • Synonyms:N-Arachidonyl maleimide;1-(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraen-1-yl-1H-pyrrole-2,5-dione;1-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-;N-Arachidonylmaleimide >=98% (HPLC)
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :492.9±34.0 °C(Predicted)
Density :0.984±0.06 g/cm3(Predicted)
storage temp. :Store at -80°C
solubility :≤30mg/ml in DMSO;30mg/ml in dimethyl formamide
form :solid
pka :-2.21±0.20(Predicted)
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

N-Arachidonyl maleimide is a highly potent and irreversible inhibitor of Monoglyceride Lipase (MAG lipase) which covalently binds to a cysteine residue located near the fatty acid binding site. N-Arachidonyl maleimide selectively prevents metabolic inactivation of 2-arachidonoylglycerol and increases the potency in vitro in mouse cerebellum.

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