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NDSB-256

NDSB-256 Structure
  • ₹10013.13 - ₹29508.95
  • Product name: NDSB-256
  • CAS: 81239-45-4
  • MF: C12H19NO3S
  • MW: 257.35
  • EINECS:999-999-2
  • MDL Number:MFCD00225018
  • Synonyms:DIMETHYLBENZYL-(3-SULFOPROPYL)AMMONIUM, INNER SALT;DIMETHYLBENZYLAMMONIUM PROPANE SULFONATE;NDSB-256;3-(BENZYLDIMETHYLAMMONIO)PROPANESULFO-;3-(n-phenylmethyl-n,n-dimethylammonio)propanesulfonate;3-(BENZYLDIMETHYLAMMONIUM)PROPANESULFONATE;3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE;3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULPHONATE
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5G
  • 25G
  • ManufacturerSigma-Aldrich(India)
  • Product number17236
  • Product description3-(Benzyldimethylammonio)propanesulfonate BioXtra, ≥99.0% (HPCE)
  • Packaging5G
  • Price₹10013.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number17236
  • Product description3-(Benzyldimethylammonio)propanesulfonate BioXtra, ≥99.0% (HPCE)
  • Packaging25G
  • Price₹29508.95
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 17236 3-(Benzyldimethylammonio)propanesulfonate BioXtra, ≥99.0% (HPCE) 5G ₹10013.13 2022-06-14 Buy
Sigma-Aldrich(India) 17236 3-(Benzyldimethylammonio)propanesulfonate BioXtra, ≥99.0% (HPCE) 25G ₹29508.95 2022-06-14 Buy

Properties

Melting point :245-248
storage temp. :-20°C Freezer
solubility :H2O: 10 mg/mL, clear, colorless
form :White solid
color :White to Off-White
BRN :9194882
Stability :Hygroscopic
CAS DataBase Reference :81239-45-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NDSB-256 is a nondetergent sulfobetaines class member. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb near UV range significantly. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis. At 1 M, NDSB-256 will restore 30% of the enzymatic activity of denatured egg white lysozyme; at 800 mM it will restore 16% of the enzymatic activity of denatured β-galactosidase.

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