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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >Serine derivatives >(+/-)-NICOTINE-METHYL-D3

(+/-)-NICOTINE-METHYL-D3

(+/-)-NICOTINE-METHYL-D3 Structure
  • ₹158326.45
  • Product name: (+/-)-NICOTINE-METHYL-D3
  • CAS: 69980-24-1
  • MF: C10H11D3N2
  • MW: 165.25
  • EINECS:
  • MDL Number:MFCD00190489
  • Synonyms:DL-NICOTINE-D3;(±)-3-[1-(Methyl-d3)-2-pyrrolidinyl)pyridine;3-[1-(Methyl-d3)-2-pyrrolidinyl]pyridine;rac-Nicotine-d3;(+/-)-NICOTINE-METHYL-D3;NICOTINE-METHYL-D3;NICOTINE-D3 (N-METHYL-D3);TRIDEUTEROMETHYL-NICOTINE
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product number489077
  • Product descriptionDL-Nicotine-(methyl-d3) 99 atom % D
  • Packaging50MG
  • Price₹158326.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 489077 DL-Nicotine-(methyl-d3) 99 atom % D 50MG ₹158326.45 2022-06-14 Buy

Properties

Boiling point :247 °C745 mm Hg(lit.)
Density :1.029 g/mL at 25 °C(lit.)
refractive index :n20/D 1.5265(lit.)
Flash point :215 °F
storage temp. :-20°C
solubility :DMF: 50 mg/ml,DMSO: 30 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml
form :Oil
color :Colourless to Yellow
Stability :May Turn Brown on Exposure to Light or Air

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H310 Fatal in contact with skin Acute toxicity,dermal Category 1, 2 Danger GHS hazard pictograms P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

(±)-Nicotine-d3 is intended for use as an internal standard for the quantification of (±)-nicotine by GC- or LC-mass spectrometry. (±)-Nicotine is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs; Kis = 481 and 11.1 nM for α3β4 and α4β2 subtypes, respectively) and possesses addictive and teratogenic properties. (?)-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode, thus nicotine is typically synthesized as (?)-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.

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