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ChemicalBook > Product Catalogue >API >Respiratory Drugs >Antitussives >NOSCAPINE HYDROCHLORIDE

NOSCAPINE HYDROCHLORIDE

NOSCAPINE HYDROCHLORIDE Structure
  • ₹6500 - ₹33265.23
  • Product name: NOSCAPINE HYDROCHLORIDE
  • CAS: 912-60-7
  • MF: C22H24ClNO7
  • MW: 449.88
  • EINECS:213-014-9
  • MDL Number:MFCD00082546
  • Synonyms:NOSCAPINE HYDROCHLORIDE;NARCOTINE HYDROCHLORIDE;,3-dioxolo(4,5-g)isoquinolin-5-yl)-,hydrochloride,(s-(r*,s*))- ;1(3h)isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1 ;1-alpha-narcotinehydrochloride ;coscopinhydrochloride ;coscotabshydrochloride ;key-tusscapinehydrochloride
5 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 50MG
  • 100MG
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberN0963
  • Product descriptionNoscapine Hydrochloride Hydrate
  • Packaging5G
  • Price₹6500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN9007
  • Product descriptionNoscapine hydrochloride hydrate analytical standard
  • Packaging5G
  • Price₹8486.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberNMID791B
  • Product descriptionNoscapine hydrochloride NMI Australia
  • Packaging100MG
  • Price₹16551.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberNMID791B
  • Product descriptionNoscapine hydrochloride NMI Australia
  • Packaging50MG
  • Price₹19863.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN9007
  • Product descriptionNoscapine hydrochloride hydrate analytical standard
  • Packaging25G
  • Price₹33265.23
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) N0963 Noscapine Hydrochloride Hydrate 5G ₹6500 2022-05-26 Buy
Sigma-Aldrich(India) N9007 Noscapine hydrochloride hydrate analytical standard 5G ₹8486.8 2022-06-14 Buy
Sigma-Aldrich(India) NMID791B Noscapine hydrochloride NMI Australia 100MG ₹16551.43 2022-06-14 Buy
Sigma-Aldrich(India) NMID791B Noscapine hydrochloride NMI Australia 50MG ₹19863.88 2022-06-14 Buy
Sigma-Aldrich(India) N9007 Noscapine hydrochloride hydrate analytical standard 25G ₹33265.23 2022-06-14 Buy

Properties

Melting point :221-223 °C(lit.)
storage temp. :2-8°C
solubility :Freely soluble in water and in ethanol (96 per cent). Aqueous solutions are slightly acid; the base may be precipitated when the solutions are allowed to stand.
color :Crystals
Merck :13,6752
EPA Substance Registry System :1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (912-60-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:

Description

Noscapine is an opioid alkaloid with antitussive and antimitotic properties. It binds to tubulin and arrests mammalian cells in mitosis at a concentration of 20 μM. Noscapine induces apoptosis (IC50 = 25 and 10 μM in HeLa cells and thymocytes, respectively) and demonstrates antitumor activity both in vitro (IC50 = 42.3 and 39.1 μM in MCF-7 and Renal 1983 cell lines, respectively) and in mice.

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