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ChemicalBook > Product Catalogue >Food Additives >Antioxidants >Nordihydroguaiaretic acid

Nordihydroguaiaretic acid

Nordihydroguaiaretic acid Structure
  • ₹5400 - ₹102707.6
  • Product name: Nordihydroguaiaretic acid
  • CAS: 500-38-9
  • MF: C18H22O4
  • MW: 302.36
  • EINECS:207-903-0
  • MDL Number:MFCD00002206
  • Synonyms:Nordihydroguaiaretic acid,95%;[-CH(CH3)CH2C6H3-1,2-(OH)2]2;Nordihydroguaiaretic acid,1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane, 4,4′-(2,3-Dimethyltetramethylene)dipyrocatechol, Masoprocol, NDGA;Nordihydroguaiaretic acid, tech. 90%;To a dihydro-nordihydroguaiaretic acid;Nordihydroguaiaretic acid, 95% 500MG;Nordihydro Guaiaretic Acid (Mixture of diastereoMers);NSC 4291
Price10 Properties Safety Information Description
10 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ALFA India

Package

  • 250MG
  • 500MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberD0800
  • Product descriptionNordihydroguaiaretic Acid
  • Packaging1G
  • Price₹5400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD0800
  • Product descriptionNordihydroguaiaretic Acid
  • Packaging5G
  • Price₹24000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number479975
  • Product descriptionNDGA - CAS 500-38-9 - Calbiochem A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC?? = 200 nM, 30 μM, and 30 μM for 5-LOX, 12-LOX, and 15-LOX, respectively
  • Packaging250MG
  • Price₹8779.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number74540
  • Product descriptionNordihydroguaiaretic acid ≥97.0% (HPLC)
  • Packaging1G
  • Price₹12124
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN5023
  • Product descriptionNordihydroguaiaretic acid ≥90% (HPLC), from Larrea divaricata (creosote bush)
  • Packaging500MG
  • Price₹17536.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN5023
  • Product descriptionNordihydroguaiaretic acid ≥90% (HPLC), from Larrea divaricata (creosote bush)
  • Packaging1G
  • Price₹28762.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number74540
  • Product descriptionNordihydroguaiaretic acid ≥97.0% (HPLC)
  • Packaging5G
  • Price₹32659.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN5023
  • Product descriptionNordihydroguaiaretic acid ≥90% (HPLC), from Larrea divaricata (creosote bush)
  • Packaging5G
  • Price₹102707.6
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-L03149-06
  • Product descriptionNordihydroguaiaretic acid, 97%
  • Packaging5g
  • Price₹29100
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-L03149-03
  • Product descriptionNordihydroguaiaretic acid, 97%
  • Packaging1g
  • Price₹6806
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D0800 Nordihydroguaiaretic Acid 1G ₹5400 2022-05-26 Buy
TCI Chemicals (India) D0800 Nordihydroguaiaretic Acid 5G ₹24000 2022-05-26 Buy
Sigma-Aldrich(India) 479975 NDGA - CAS 500-38-9 - Calbiochem A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC?? = 200 nM, 30 μM, and 30 μM for 5-LOX, 12-LOX, and 15-LOX, respectively 250MG ₹8779.99 2022-06-14 Buy
Sigma-Aldrich(India) 74540 Nordihydroguaiaretic acid ≥97.0% (HPLC) 1G ₹12124 2022-06-14 Buy
Sigma-Aldrich(India) N5023 Nordihydroguaiaretic acid ≥90% (HPLC), from Larrea divaricata (creosote bush) 500MG ₹17536.5 2022-06-14 Buy
Sigma-Aldrich(India) N5023 Nordihydroguaiaretic acid ≥90% (HPLC), from Larrea divaricata (creosote bush) 1G ₹28762.03 2022-06-14 Buy
Sigma-Aldrich(India) 74540 Nordihydroguaiaretic acid ≥97.0% (HPLC) 5G ₹32659.03 2022-06-14 Buy
Sigma-Aldrich(India) N5023 Nordihydroguaiaretic acid ≥90% (HPLC), from Larrea divaricata (creosote bush) 5G ₹102707.6 2022-06-14 Buy
ALFA India ALF-L03149-06 Nordihydroguaiaretic acid, 97% 5g ₹29100 2022-05-26 Buy
ALFA India ALF-L03149-03 Nordihydroguaiaretic acid, 97% 1g ₹6806 2022-05-26 Buy

Properties

Melting point :184-186 °C (lit.)
Boiling point :363.4°C (rough estimate)
Density :1.0772 (rough estimate)
refractive index :1.4230 (estimate)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
form :Powder
pka :9.56±0.10(Predicted)
color :White to off-white
Water Solubility :slightly soluble
Merck :14,6693
BRN :2056825
Stability :Stable. Incompatible with oxidizing agents.
LogP :4.640 (est)
CAS DataBase Reference :500-38-9(CAS DataBase Reference)
NIST Chemistry Reference :Pyrocatechol, 4,4'-(2,3-dimethyltetramethylene)di-(500-38-9)
EPA Substance Registry System :Nordihydroguaiaretic acid (500-38-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Nordihydroguaiaretic acid (NDGA) is a grayish-white crystalline compound that was widely used as an antioxidant in animal fats in the 1950s and 1960s. It possesses phenolic properties similar to gallates, including their advantages and disadvantages. Besides the isolation of natural material (resinous exudate of creosote bush), NDGA has also been chemically synthesized. As the result of unfavorable toxicological findings, NDGA is prohibited from use in the US. More specifically, NDGA is a potent lipoxygenase inhibitor which interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carbox- ylesterase,and,to a lesser extent, cyclooxygenase.

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Suppliers and manufacturers

Hebei Yanxi Chemical Co., Ltd.
Nordihydroguaiaretic acid
₹40.00 /1kg
Nordihydroguaiaretic acid CAS:500-38-9
GLR Innovations chromsynth pvt ltd Myosynth Laboratories Pvt Ltd CHEMSWORTH CLEARSYNTH LABS LTD. A.J Chemicals TCI Chemicals (India) Pvt. Ltd. Alfa Aesar Myosynth Laboratories Private Limited