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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Contraceptives >Norgestimate

Norgestimate

Norgestimate Structure
  • ₹9038.88 - ₹21812.38
  • Product name: Norgestimate
  • CAS: 35189-28-7
  • MF: C23H31NO3
  • MW: 369.5
  • EINECS:
  • MDL Number:MFCD00867874
  • Synonyms:13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl acetate;(17R)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one oxime;Norgestimate (200 mg);(17α)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-OxiMe;(17a)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-Oxime;D-138;(17-alpha)-17-(acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one3-oxime ;18,19-dinorpregn-4-en-20-yn-3-one,17-(acetyloxy)-13-ethyl-,3-oxime,(17-alpha
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product number94497
  • Product descriptionNorgestimate analytical standard
  • Packaging50MG
  • Price₹9038.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2119
  • Product descriptionNorgestimate Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹21812.38
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 94497 Norgestimate analytical standard 50MG ₹9038.88 2022-06-14 Buy
Sigma-Aldrich(India) PHR2119 Norgestimate Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹21812.38 2022-06-14 Buy

Properties

Melting point :216°C
alpha :D25 +110°
Boiling point :497.9±45.0 °C(Predicted)
Density :1.22±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO: soluble5mg/mL (clear solution)
form :powder
pka :12.21±0.60(Predicted)
color :white to beige
optical activity :[α]/D 43±3°, c = 1 in chloroform
BRN :6440219
Stability :Hygroscopic
CAS DataBase Reference :35189-28-7
EPA Substance Registry System :18,19-Dinorpregn-4-en-20-yn-3-one, 17-(acetyloxy)-13-ethyl-, 3-oxime, (17.alpha.)- (35189-28-7)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P201 Obtain special instructions before use.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Progesterone is a steroid secreted by the corpus luteum and placenta. It is responsible for preparing the uterine lining for implantation of a fertilized ovum and to maintain pregnancy. Norgestimate is a synthetic progesterone analog (i.e., a progestin) that acts as a prodrug to norelgestromin, the primary active metabolite, and levonorgestrel . It is deacetylated in the intestine and liver to form the two active metabolites. Norgestimate selectively binds the progesterone receptor and is androgenically neutral. A USP-approved grade of norgestimate is formulated in combination with ethynyl estradiol and provided under the trade name Ortho-Tri-Cyclen? for use as an oral contraceptive.

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