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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >OLIGOMYCIN A

OLIGOMYCIN A

OLIGOMYCIN A Structure
  • ₹26900.13
  • Product name: OLIGOMYCIN A
  • CAS: 579-13-5
  • MF: C45H74O11
  • MW: 791.06
  • EINECS:209-437-3
  • MDL Number:MFCD00065705
  • Synonyms:OLIGOMYCIN A, STREPTOMYCES DIASTATOCHROMOGENES;OLIGOMYCIN A;OLIGOMYCIN, STREPTOMYCES DIASTATOCHROMOGENES;Oligomycin A fromStreptomyces diastatochromogenes;(1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione;(1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonaMethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonaco;MCH 32;AOligoMyci
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number75351
  • Product descriptionOligomycin A ≥99% (HPLC)
  • Packaging5MG
  • Price₹26900.13
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 75351 Oligomycin A ≥99% (HPLC) 5MG ₹26900.13 2022-06-14 Buy

Properties

Melting point :150-151℃
Boiling point :886.3±65.0 °C(Predicted)
Density :1.14
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO, ethanol or acetone
pka :12.52±0.70(Predicted)
form :powder
color :white to off-white
Merck :13,6902
BRN :5702132
InChIKey :MNULEGDCPYONBU-WMBHJXFZSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.

Description

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin A, a dominant analog of the isomers, is an inhibitor of mitochondrial F1FO ATP synthase that induces apoptosis in a variety of cell types (average GI50 = 270 nM). Oligomycin A exhibits antifungal, antitumor, and nematocidal activities, but has poor solubility in water and other biocompatible solvents, which limits its clinical application.

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