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ChemicalBook > Product Catalogue >Catalyst and Auxiliary >Antioxidant >Oleoyl Ethanolamide

Oleoyl Ethanolamide

Oleoyl Ethanolamide Structure
  • ₹22234.55 - ₹45778.93
  • Product name: Oleoyl Ethanolamide
  • CAS: 111-58-0
  • MF: C20H39NO2
  • MW: 325.53
  • EINECS:203-884-8
  • MDL Number:MFCD00045972
  • Synonyms:N-(2-hydroxyethyl)-,(Z)-9-Octadecenamide ;OLEIC ACID-2,6-DIISOPROPYL ANILIDE;N-[2,6-BIS(1-METHYLETHYL)PHENYL]-9Z-OCTADECENAMIDE;N-Oleoylethanolamine, ~98%;9Z-OCTADECENOYLETHANOLAMIDE;C18:1 ANANDAMIDE;C18:1 anandamide;Oleoylmonoethanolamide ;Oleyl monoethanolamide
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberO0383
  • Product descriptionN-Oleoylethanolamine ~98% (TLC)
  • Packaging10MG
  • Price₹22234.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO0383
  • Product descriptionN-Oleoylethanolamine ~98% (TLC)
  • Packaging25MG
  • Price₹45778.93
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) O0383 N-Oleoylethanolamine ~98% (TLC) 10MG ₹22234.55 2022-06-14 Buy
Sigma-Aldrich(India) O0383 N-Oleoylethanolamine ~98% (TLC) 25MG ₹45778.93 2022-06-14 Buy

Properties

Melting point :63-64 °C
Boiling point :496.4±38.0 °C(Predicted)
Density :0.915±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml)
pka :14.49±0.10(Predicted)
form :White solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :InChI=1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
InChIKey :BOWVQLFMWHZBEF-KTKRTIGZSA-N
SMILES :C(NCCO)(=O)CCCCCCC/C=C\CCCCCCCC
LogP :6.406 (est)
CAS DataBase Reference :111-58-0(CAS DataBase Reference)
EPA Substance Registry System :9-Octadecenamide, N-(2-hydroxyethyl)-, (9Z)- (111-58-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Oleoyl ethanolamide (OEA) is an analog of the endocannabinoid AEA found in brain tissue and in chocolate. It is one of the long chain fatty acid ethanolamides that accumulates rapidly in infarcted tissue, but its biosynthesis is reduced in the intestine of rats following food deprivation. OEA is an endogenous, potent agonist for PPARα, exhibiting an EC50 value of 120 nM in a transactivation assay. Systemic administration of OEA suppresses food intake and reduces weight gain in rats (10 mg/kg intraperitoneally) and PPARα wild-type mice, but not in PPARα knockout mice. These data indicate that OEA regulates food intake by a PPARα-mediated mechanism.

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