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ChemicalBook > Product Catalogue >API >Blood System Drugs >Anticoagulant and Antiplatelet Drugs >Ozagrel

Ozagrel

Ozagrel Structure
  • ₹0
  • Product name: Ozagrel
  • CAS: 82571-53-7
  • MF: C13H12N2O2
  • MW: 228.25
  • EINECS:919-112-4
  • MDL Number:MFCD00868231
  • Synonyms:(E)-4-(1-Imidazoylmethyl)cinnamic acid;2-Propenoic acid, 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-, (2E)-;(E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]propenoic acid;(E)-3-[p-(1H-Imidazol-1-ylmethyl)phenyl]acrylic acid;3-[4-(1H-IMIDAZOL-1-YLMETHYL)PHENYL]-2E-PROPENOIC ACID;Ozagrel API;Ozagrel(OKY-046);(2E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :223-224°
Boiling point :468.0±25.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO : 50 mg/mL (219.06 mM; Need ultrasonic)
form :Powder
pka :4.43±0.10(Predicted)
color :White to off-white
CAS DataBase Reference :82571-53-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Inhibition of thromboxane synthase (TXAS), especially in human platelets, has been a clinical objective for many years. 1-Alkyl (N-alkyl)-imidazole derivatives have been recognized as TXAS inhibitors since the early 1980s. Ozagrel is a 1-alkyl imidazole derivative that acts as a selective inhibitor of TXAS with an IC50 of 11 nM. The beneficial effects of TXAS inhibition by ozagrel include improved motor coordination after experimental stroke, and antihypertensive effects in spontaneously hypertensive rats.

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