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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Food and cosmetics standards >PAXILLINE

PAXILLINE

PAXILLINE Structure
  • ₹38385.45 - ₹68489.78
  • Product name: PAXILLINE
  • CAS: 57186-25-1
  • MF: C27H33NO4
  • MW: 435.56
  • EINECS:637-206-0
  • MDL Number:MFCD00083464
  • Synonyms:(2R)-5,6,6aα,7,12,12b,12c,13,14,14aβ-Decahydro-4bβ-hydroxy-2-(1-hydroxy-1-methylethyl)-12bβ,12cα-dimethyl-2H-1-benzopyrano[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one;2h-1-benzopyrano(5’,6’:6,7)indeno(1,2-b)indol-3(4bh)-one,5,6,6a,7,12,12b,12c,1 ;4b-beta,6a-alpha,12b-beta,12c-alpha,14a-beta)-2-alph ;paxilline from penicillium paxilli;PAXILINE;Paxicillin;(2R,4bS,6aS,12bS,12cR,14aS)-4b-Hydroxy-2-(1-hydroxy-1-methylethyl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5′,6′:6,7]indeno[1,2-b]indol-3(4bH)-one solution;Paxilline solution
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberP2928
  • Product descriptionPaxilline powder, ≥98% (HPLC)
  • Packaging5MG
  • Price₹38385.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP2928
  • Product descriptionPaxilline powder, ≥98% (HPLC)
  • Packaging10MG
  • Price₹68489.78
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) P2928 Paxilline powder, ≥98% (HPLC) 5MG ₹38385.45 2022-06-14 Buy
Sigma-Aldrich(India) P2928 Paxilline powder, ≥98% (HPLC) 10MG ₹68489.78 2022-06-14 Buy

Properties

Flash point :2℃
storage temp. :2-8°C
solubility :Soluble in DMSO, acetone or chloroform.
form :powder
color :faint yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Paxilline is an indole diterpene from fungi which potently and reversibly inhibits large conductance Ca2+-activated K+ (BKCa) channels, as shown in patch clamp (Ki = 1.9 nM) and whole smooth muscle cell studies (Ki = 35.7 nM). It also enhances the binding of charybdotoxin, a peptidyl neurotoxin, to BKCa channels. Paxilline is currently used to evaluate the role of BKCa channels in various cell processes and responses.

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