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PENITREM A

PENITREM A Structure
  • ₹30223.4 - ₹101257.05
  • Product name: PENITREM A
  • CAS: 12627-35-9
  • MF: C37H44ClNO6
  • MW: 634.2
  • EINECS:634-132-0
  • MDL Number:MFCD12547934
  • Synonyms:TREMORTIN A;Penitrem A from Penicillium paxilli;PENITREM A;PENITREM A, PENICILLIUM PAXILLI;penitrem A from penicillium palitans;Penitrem A Nsc354845;JDUWHZOLEDOQSR-JKPSMKLGSA-N;2R,3S,3aR,4aS,4bS,6aR,7S,7dR,8R,9aR,14bS,14cR,16aS)-12-chloro-3,3a,6a,8,9,9a,10,11,14,14b,14c,15,16,16a-tetradecahydro-14b,14c,17,17-tetramethyl-10-methylene-2-(1-methylethenyl)-7,8-(epoxymethano)-2H,6H-cyclobuta[5,6]benz[1,2-e]oxireno[4',4'a]-1-benzopyrano[5',6':6,7]indeno[1,2-b]indole-3,4b,7d(5H,7H)-triol
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberP3053
  • Product descriptionPenitrem A ≥95% (HPLC and TLC)
  • Packaging1MG
  • Price₹30223.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP3053
  • Product descriptionPenitrem A ≥95% (HPLC and TLC)
  • Packaging5MG
  • Price₹101257.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) P3053 Penitrem A ≥95% (HPLC and TLC) 1MG ₹30223.4 2022-06-14 Buy
Sigma-Aldrich(India) P3053 Penitrem A ≥95% (HPLC and TLC) 5MG ₹101257.05 2022-06-14 Buy

Properties

Melting point :238°C
Density :1.0241 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 6 mg/ml)
form :White solid.
pka :13.22±0.70(Predicted)
color :Amorphous solid
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

Penitrem A is a tremorgenic fungal toxin that acts as an inhibitor of the large conductance calcium-activated potassium channel BKCa (SLO1, Maxi-K, KCa1.1), inhibiting the binding of charybdotoxin with an IC50 value of 1.7 μM. It is currently used to evaluate the role of BKCa-mediated potassium flux in various cell processes and responses.

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