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ChemicalBook > Product Catalogue >Natural Products >Phenols >PICEATANNOL

PICEATANNOL

PICEATANNOL Structure
  • ₹8310 - ₹119572.95
  • Product name: PICEATANNOL
  • CAS: 10083-24-6
  • MF: C14H12O4
  • MW: 244.24
  • EINECS:600-132-4
  • MDL Number:MFCD00221715
  • Synonyms:TRANS-3,3',4,5'-TETRAHYDROXYSTILBENE;PICEATANNOL;PICEATANNOL (3,3',4,5'-TETRAHYDROXY-TRAN;(e)-4-[2-(3,5dihydroxyphenyl)ethenyl]1,2-benzenediol;4-[2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol;trans-Piceatannol;(E)-3,3',4,5'-Tetrahydroxystilbene;(E)-Piceatannol
5 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 25MG
  • 100MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberP1928
  • Product descriptionPiceatannol
  • Packaging100MG
  • Price₹10800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1928
  • Product descriptionPiceatannol
  • Packaging1G
  • Price₹26000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number527948
  • Product descriptionPiceatannol - CAS 10083-24-6 - Calbiochem A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC
  • Packaging1MG
  • Price₹8310
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP0453
  • Product descriptionPiceatannol powder
  • Packaging5MG
  • Price₹35841.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP0453
  • Product descriptionPiceatannol powder
  • Packaging25MG
  • Price₹119572.95
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P1928 Piceatannol 100MG ₹10800 2022-05-26 Buy
TCI Chemicals (India) P1928 Piceatannol 1G ₹26000 2022-05-26 Buy
Sigma-Aldrich(India) 527948 Piceatannol - CAS 10083-24-6 - Calbiochem A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC 1MG ₹8310 2022-06-14 Buy
Sigma-Aldrich(India) P0453 Piceatannol powder 5MG ₹35841.58 2022-06-14 Buy
Sigma-Aldrich(India) P0453 Piceatannol powder 25MG ₹119572.95 2022-06-14 Buy

Properties

Melting point :223.0-227.0 °C
Boiling point :108°C/0.04mmHg(lit.)
Density :1.1245 (rough estimate)
refractive index :1.5190 (estimate)
storage temp. :2-8°C
solubility :H2O: 0.5 mg/mL
form :powder
pka :9.17±0.10(Predicted)
color :light tan to yellow
λmax :323nm(MeOH)(lit.)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
LogP :2.690 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

Piceatannol is a catechol-type polyphenol. The compound has been shown to act as a protein-tyrosine kinase inhibitor, and preferentially inhibits Syk in comparison to Lyn in in vitro kinase assays. In MCF-10A cell studies, Piceatannol inhibited phorbol ester-induced NF-κB activation and cyclooxygenase-2 expression. Research indicates that Piceatannol can upregulate Fas and FasL through AFT2 and Ca2+/p38α MAPK-mediated activation of c-Jun pathways. Identified as a potential inhibitor of PKA, PKC, MYLK, Lck, and IKKβ as well as an activator of SIRT1. SIRT1 is an NAD+ dependent deacetylase that is known to target histone H4. Piceatannol is an inhibitor of CaMK, JNK, IKKα and PI 3-kinase. Piceatannol is an activator of caspase-3.

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