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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antipsychotics >Pimozide

Pimozide

Pimozide Structure
  • ₹7070 - ₹18326.73
  • Product name: Pimozide
  • CAS: 2062-78-4
  • MF: C28H29F2N3O
  • MW: 461.55
  • EINECS:218-171-7
  • MDL Number:MFCD00055081
  • Synonyms:PIMOZIDE;1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinon ;1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinone ;1-(4,4-bis(p-fluorophenyl)butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine ;mcn-jr-6238 ;1-[1-(4,4-BIS[4-FLUOROPHENYL]BUTYL)-4-PIPERIDINYL]-1,3-DIHYDRO-2H-BENZ-IMIDAZOL-2-ONE;3-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidyl)-1H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1-1-4,4-bis(4-fluorophenyl)butyl-4-piperidinyl-1,3-dihydro-
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • 500MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product number573110
  • Product descriptionSTAT5 Inhibitor III, Pimozide - CAS 2062-78-4 - Calbiochem The STAT5 Inhibitor III, Pimozide, also referenced under CAS 2062-78-4, controls the biological activity of STAT5. This small molecule/inhibitor is pr
  • Packaging100MG
  • Price₹7070
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP1793
  • Product descriptionPimozide
  • Packaging500MG
  • Price₹10327.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP1793
  • Product descriptionPimozide
  • Packaging1G
  • Price₹18326.73
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 573110 STAT5 Inhibitor III, Pimozide - CAS 2062-78-4 - Calbiochem The STAT5 Inhibitor III, Pimozide, also referenced under CAS 2062-78-4, controls the biological activity of STAT5. This small molecule/inhibitor is pr 100MG ₹7070 2022-06-14 Buy
Sigma-Aldrich(India) P1793 Pimozide 500MG ₹10327.05 2022-06-14 Buy
Sigma-Aldrich(India) P1793 Pimozide 1G ₹18326.73 2022-06-14 Buy

Properties

Melting point :214-218°
Density :1.1763 (estimate)
storage temp. :2-8°C
solubility :DMSO: 18 mg/mL
pka :7.32(at 25℃)
form :White solid
color :Off-White to Light Orange
Water Solubility :2.9mg/L(30 ºC)
CAS DataBase Reference :2062-78-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Pimozide is an antipsychotic compound that displays high affinity for dopamine receptors (Kis = 2.4, 0.2, and 1.8 nM for D2, D3, and D4, respectively). It also has actions as an antagonist, inverse agonist, or channel blocker, with lower affinities, at serotonin, α-adrenergic, muscarinic cholinergic, and histamine receptors and calcium and sodium channels. Pimozide is metabolized in the liver primarily by cytochrome P450 (CYP) 3A4, but CYP2D6, an isoform known to be genetically variable, can also affect metabolism. Pimozide has diverse neuropathological applications, including in Tourette syndrome.

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