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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Bulk Drug Intermediates >PROSTAGLANDIN A2

PROSTAGLANDIN A2

PROSTAGLANDIN A2 Structure
  • ₹0
  • Product name: PROSTAGLANDIN A2
  • CAS: 13345-50-1
  • MF: C20H30O4
  • MW: 334.45
  • EINECS:634-333-3
  • MDL Number:MFCD00077859
  • Synonyms:(5Z)-7-[(1R,2S)-2-[(1E,3S)-3-Hydroxy-1-octenyl]-5-oxo-3-cyclopenten-1-yl]-5-heptenoic acid;(5Z,13E,15S)-15-Hydroxy-9-oxo-5,10,13-prostatrien-1-oic acid;Prostaglandin A2 solution,(5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid, PGA2;PGA2 (Prostaglandin A2);9-OXO-15S-HYDROXY-PROSTA-5Z,10,13E-TRIEN-1-OIC ACID;[5Z,13E,15S]-15-HYDROXY-9-OXOPROSTA-5,10,13-TRIEN-1-OIC ACID;(+)-prostaglandina(sup2) ;(155)-pga2
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :391.24°C (rough estimate)
Density :1.0332 (rough estimate)
refractive index :1.4434 (estimate)
Flash point :-9 °C
storage temp. :−20°C
solubility :Acetonitrile (Slightly), Chloroform (Slightly), Water (Slightly)
form :Neat oil.
pka :4.75±0.10(Predicted)
color :Colourless to Dark Yellow
Stability :Stable under recommended storage conditions., Stable Under Recommended Storage C

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity. At a 25 μM concentration, PGA2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase. It has also been shown to act as a vasodilator with natriuretic properties.

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