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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Prostaglandin drugs >Prostaglandin E1

Prostaglandin E1

Prostaglandin E1 Structure
  • ₹17114.33 - ₹100488.48
  • Product name: Prostaglandin E1
  • CAS: 745-65-3
  • MF: C20H34O5
  • MW: 354.49
  • EINECS:212-017-2
  • MDL Number:MFCD00077860
  • Synonyms:Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11a,13E,15S)-;(8S,11S,12S,13E,15R)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid;ent-PGE1;Alprostadil (PGE1)／Prostaglandin E1;Prostaglandin E1 or AIPROSTADIL;l-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoicacid ;l-cyclopentaneheptanoicaci ;l-pge1
Price6 Properties Safety Information Description
6 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberP5515
  • Product descriptionProstaglandin E1 ≥98% (HPLC), synthetic
  • Packaging1MG
  • Price₹17114.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7527
  • Product descriptionProstaglandin E1 powder, γ-irradiated, BioXtra, suitable for cell culture
  • Packaging1MG
  • Price₹29822.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP5515
  • Product descriptionProstaglandin E1 ≥98% (HPLC), synthetic
  • Packaging5MG
  • Price₹49199.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7527
  • Product descriptionProstaglandin E1 powder, γ-irradiated, BioXtra, suitable for cell culture
  • Packaging10MG
  • Price₹50769.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP5515
  • Product descriptionProstaglandin E1 ≥98% (HPLC), synthetic
  • Packaging10MG
  • Price₹65740.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP8908
  • Product descriptionProstaglandin E1 synthetic, powder, BioReagent, suitable for cell culture
  • Packaging10MG
  • Price₹100488.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) P5515 Prostaglandin E1 ≥98% (HPLC), synthetic 1MG ₹17114.33 2022-06-14 Buy
Sigma-Aldrich(India) P7527 Prostaglandin E1 powder, γ-irradiated, BioXtra, suitable for cell culture 1MG ₹29822.88 2022-06-14 Buy
Sigma-Aldrich(India) P5515 Prostaglandin E1 ≥98% (HPLC), synthetic 5MG ₹49199.63 2022-06-14 Buy
Sigma-Aldrich(India) P7527 Prostaglandin E1 powder, γ-irradiated, BioXtra, suitable for cell culture 10MG ₹50769.25 2022-06-14 Buy
Sigma-Aldrich(India) P5515 Prostaglandin E1 ≥98% (HPLC), synthetic 10MG ₹65740.23 2022-06-14 Buy
Sigma-Aldrich(India) P8908 Prostaglandin E1 synthetic, powder, BioReagent, suitable for cell culture 10MG ₹100488.48 2022-06-14 Buy

Properties

Melting point :115-116 °C
alpha :-64 º (c=1.0, C2H5OH)
Boiling point :407.69°C (rough estimate)
Density :1.0458 (rough estimate)
refractive index :1.6120 (estimate)
storage temp. :-20°C
solubility :ethanol: 1 mg/mL
form :powder
pka :pKa 4.85± 0.07(H2O,t=25±0.1,I=0.1(NaCl)) (Uncertain)
color :White to off-white
Water Solubility :insoluble
Merck :13,7968
BRN :5294062
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :GMVPRGQOIOIIMI-DWKJAMRDSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

PGE1 is the theoretical cyclooxygenase metabolite of dihomo-γ-linolenic acid (DGLA), but it is virtually undetectable in the plasma of normal humans or other animals. Its pharmacology includes vasodilation, hypotension, and anti-platelet activities. The IC50 of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM. The vasorelaxant and anti-hypertensive effects of PGE1 are used to treat male erectile dysfunction and to provide emergency vasodilation of the patent ductus arteriosus in infants whose cardiac anomalies require pulmonary shunting for survival. In human males, the intracavernosal effective dose range for PGE1 is 2 to 80 μg, and the transurethral range is 125 to 1,000 μg.

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Suppliers and manufacturers

ANVI Pharma Aspen Biopharma Labs Pvt Ltd Manus Aktteva Euroasia Trans Continental CLEARSYNTH LABS LTD. A.J Chemicals Alfa Aesar Pharmaffiliates Analytics and Synthetics P. Ltd Aspen Biopharma Labs Private Limited Anvi Pharmaceuticals