Prostaglandin E1
Prostaglandin E1
- CAS:
- 745-65-3
- MF:
- C20H34O5
- MW:
- 354.49
Suppliers by country/region
Company Type
Properties
- Melting point:
- 115-116 °C
- alpha
- -64 º (c=1.0, C2H5OH)
- Boiling point:
- 407.69°C (rough estimate)
- Density
- 1.0458 (rough estimate)
- refractive index
- 1.6120 (estimate)
- storage temp.
- -20°C
- solubility
- ethanol: 1 mg/mL
- form
- powder
- pka
- pKa 4.85± 0.07(H2O,t=25±0.1,I=0.1(NaCl)) (Uncertain)
- color
- White to off-white
- Water Solubility
- insoluble
- Merck
- 13,7968
- BRN
- 5294062
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
- InChIKey
- GMVPRGQOIOIIMI-DWKJAMRDSA-N
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P301+P310+P330
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38-61
- Safety Statements
- 36-26
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- GY4569800
- F
- 8-10
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29375000
Use
Prostaglandin E1 (Prostaglandin E1), also known as alprostadil. Prostaglandin E1 is widely present in the body of biologically active substances, as one of the prostaglandin family, it is a recognized endogenous physiologically active substances. Prostaglandin E1 acts directly on vascular smooth muscle, dilates blood vessels, increases blood flow, improves microcirculation perfusion; and inhibits platelet aggregation and thromboxane A2 production, inhibits atherosclerosis, lipid plaque and immune complex formation; it also owns following effects: the expansion of the periphery small blood vessels and coronary arteries, reduction of peripheral vascular resistance and blood pressure, protection platelet membrane against thrombosis; protection the ischemic myocardium, reducing myocardial infarct size; anti-heart failure; renal vascular dilation, increased renal blood flow, removal of non-protein nitrogen, regulating sodium and water balance, with a diuretic and renal-protecting function. t1/2 is 5~10min. 68% is excreted by renal after hepatic metabolism . Clinical usage includes angina pectoris, myocardial infarction, pulmonary hypertension, chronic arterial occlusion. The above information is edited by the chemicalbook of Tian Ye.
7 India supplier list of "Prostaglandin E1"
![](/images/pro-3.jpg)
- Product Name:Alprostadil
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
![](/images/pro-3.jpg)
- Product Name:Alprostadil
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
![](/images/pro-3.jpg)
- Product Name:ProstaglandinE1
- Products Intro:Brand:sigma aldrich | Product Number:P5515 | Purity:≥98%(HPLC),synthetic
- Company Type: Trader
- Country/Region: Bangalore,INDIA
![](/images/pro-3.jpg)
- Product Name:Alprostadil
- Products Intro:Brand:synzeal | Product Number:187488757
- Company Type: Trader
- Country/Region: Gujarat,INDIA
![](/images/pro-3.jpg)
- Product Name:Prostaglandin E1
- Company Type: Reagent
- Country/Region: Haryana,INDIA
![](/images/pro-3.jpg)
- Product Name:Alprostadil
- Company Type: Reagent
- Country/Region: Punjab,INDIA