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CARBACYCLIN

CARBACYCLIN

CAS:
69552-46-1
MF:
C21H34O4
MW:
350.49

Company Type

Properties

Melting point:
65-67℃
Boiling point:
514.8±50.0 °C(Predicted)
Density 
1.177±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble at 20mg/ml in ethanol.
form 
Solid
pka
4.77±0.10(Predicted)
color 
White to off-white

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
Hazard statements 
H302-H312-H332
Precautionary statements 
P261-P280h-P301+P312a-P304+P340-P321-P501a
Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
22-36
WGK Germany 
3

Use

Carbacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex vivo platelet aggregation, but the effect persists only 10 minutes after termination of the infusion. Carbacyclin is a stable analog of PGI2. Carbacyclin inhibits platelet aggregation with 10% of the molar potency exhibited by PGI2. The ED50 of Carbacyclin for the in vitro inhibition of ADP-induced platelet aggregation in human PRP is 47 nM. It was also shown to effect terminal differentiation of preadipose into adipose cells and enhance the expression of angiotensinogen and adipose fatty acid binding protein with an EC50 of about 0.5 μM.

0 India supplier list of "CARBACYCLIN"

  • Product Name:Carbacyclin
  • Products Intro:Brand:clearsynth | Product Number:CS-T-71304
  • Company Type: Trader
  • Country/Region: Hyderabad,INDIA
  • Product Name:Carbacyclin;Carbaprostacyclin;Carba-PGI2
  • Products Intro:Purity: 98.00% | Package: 100 mg;500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • Product Name:Carbacyclin
  • Products Intro:Package: 100μg;233USD
  • Company Type: Reagent
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • Product Name:CARBACYCLIN
  • Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Pharmaceutical intermediate
  • Product Name:Carbacyclin (Carbocyclic PGI)
  • Products Intro:Purity: >99% | Package: $395.9/1mg;Bulk package | CustNote: >99%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
  • 0.5mg$150.00
  • Product Name:Carbacyclin
  • Products Intro:Brand:Alfa Aesar | Product Number:J67199 | Purity:99%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • 500 µg$125.00
  • Product Name:Carbaprostacyclin
  • Products Intro:Brand:Caymanchem | Product Number:18210 | Purity:≥98%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:Carbacyclin
  • Products Intro:Brand:glenthamls | Product Number:GL3664
  • Company Type: Trader
  • Country/Region: UNITED KINGDOM
  • 1mg$400.00
  • Product Name:Carbacyclin
  • Products Intro:Brand:ChemScene | Product Number:CS-0045198 | Purity:>99.0%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:(5E)-5-[(3aS,4S,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoicacid
  • Products Intro:Brand:a2bchem | Product Number:AX18783 | Purity:≥99%
  • Company Type: Trader
  • Country/Region: UNITED STATES

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CARBACYCLIN
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