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ChemicalBook > Product Catalogue >Organic Chemistry >Amides >Sulfonic acids amino compound >PROTOPORPHYRINATO ZINC

PROTOPORPHYRINATO ZINC

PROTOPORPHYRINATO ZINC Structure
  • ₹8310 - ₹69160.93
  • Product name: PROTOPORPHYRINATO ZINC
  • CAS: 15442-64-5
  • MF: C34H31N4O4Zn-
  • MW: 625.03
  • EINECS:239-455-7
  • MDL Number:MFCD00011612
  • Synonyms:PROTOPORPHYRINATO ZINC;dihydrogen [3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]zincate(4-);Zinc protoporphyrin trihydrate;Zinc protoporphyrin trihydrate, 95+%;Zinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem;PROTOPORPHYRINATO ZINC ISO 9001:2015 REACH;Zinc Protoporphyrin IX DISCONTINUED, offer Z439970;ZnPP
5 prices
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Brand

  • Sigma-Aldrich(India)
  • Sigma-Aldrich

Package

  • 25MG
  • 50MG
  • 250MG
  • ManufacturerSigma-Aldrich(India)
  • Product number282820
  • Product descriptionProtoporphyrin IX zinc(II) guanylate cyclase inhibitor
  • Packaging250MG
  • Price₹69160.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number282820
  • Product descriptionProtoporphyrin IX zinc(II) guanylate cyclase inhibitor
  • Packaging50MG
  • Price₹19961.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number691550-M
  • Product descriptionZinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin.
  • Packaging25MG
  • Price₹8310
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number282820
  • Product descriptionProtoporphyrin IX zinc(II) guanylate cyclase inhibitor
  • Packaging250MG
  • Price₹69160.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number282820
  • Product descriptionProtoporphyrin IX zinc(II) guanylate cyclase inhibitor
  • Packaging50MG
  • Price₹19961.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 282820 Protoporphyrin IX zinc(II) guanylate cyclase inhibitor 250MG ₹69160.93 2022-06-14 Buy
Sigma-Aldrich(India) 282820 Protoporphyrin IX zinc(II) guanylate cyclase inhibitor 50MG ₹19961.3 2022-06-14 Buy
Sigma-Aldrich(India) 691550-M Zinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin. 25MG ₹8310 2022-06-14 Buy
Sigma-Aldrich 282820 Protoporphyrin IX zinc(II) guanylate cyclase inhibitor 250MG ₹69160.93 2022-06-14 Buy
Sigma-Aldrich 282820 Protoporphyrin IX zinc(II) guanylate cyclase inhibitor 50MG ₹19961.3 2022-06-14 Buy

Properties

RTECS :ZG9210300
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO : 50 mg/mL (79.87 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :Crystalline
color :Dark red to purple
Water Solubility :Insoluble in water. Soluble in ethanol, and DMSO, pyridine, or dimethyl formamide.
Stability :Hygroscopic
EPA Substance Registry System :Zincate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-.kappa.N21,.kappa.N22,.kappa.N23,.kappa.N24]-, dihydrogen, (SP-4-2)- (15442-64-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Zinc protoporphyrin-9 (ZnPPIX) is an endogenous metabolite formed during heme biosynthesis under conditions of iron insufficiency or impaired iron utilization. It also regulates heme catabolism through competitive inhibition of heme oxygenase, the rate-limiting enzyme in the heme degradation pathway that produces bilirubin and carbon monoxide. ZnPPIX has been shown to inhibit 80% of soluble guanylyl cyclase basal activity at 2.5 μM and to inactivate the NOS isoforms nNOS, iNOS, and eNOS with IC50 values of 0.8, 4, and 5 μM, respectively. ZnPPIX has been used to assess iron status and to diagnose iron disorders and has shown therapeutic potential in hyperbilirubinemia.

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