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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Peripheral vasodilators >Phentolamine mesilate

Phentolamine mesilate

Phentolamine mesilate Structure
  • ₹2700 - ₹38915.88
  • Product name: Phentolamine mesilate
  • CAS: 65-28-1
  • MF: C18H23N3O4S
  • MW: 377.46
  • EINECS:200-604-6
  • MDL Number:MFCD00134201
  • Synonyms:REGITIN;REGITIN MESYLATE;PHENTOLAMINE MESILATE;PHENTOLAMINE METHANESULFONATE;PHENTOLAMINE METHANESULFONATE SALT;VASOMAX;m-(n-(2-imidazolin-2-ylmethyl)-p-toluidino)-phenomonomethanesulfonate(sal ;phentolaminemethanesulphonate
5 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)

Package

  • 100MG
  • 500MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7561
  • Product descriptionPhentolamine methanesulfonate salt ≥98% (TLC), powder
  • Packaging100MG
  • Price₹9103.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1403
  • Product descriptionPhentolamine Mesylate Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹10002.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP7561
  • Product descriptionPhentolamine methanesulfonate salt ≥98% (TLC), powder
  • Packaging500MG
  • Price₹38915.88
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1985
  • Product descriptionPhentolamine Mesylate
  • Packaging1G
  • Price₹4100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1985
  • Product descriptionPhentolamine Mesylate
  • Packaging100MG
  • Price₹2700
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) P7561 Phentolamine methanesulfonate salt ≥98% (TLC), powder 100MG ₹9103.83 2022-06-14 Buy
Sigma-Aldrich(India) PHR1403 Phentolamine Mesylate Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹10002.3 2022-06-14 Buy
Sigma-Aldrich(India) P7561 Phentolamine methanesulfonate salt ≥98% (TLC), powder 500MG ₹38915.88 2022-06-14 Buy
TCI Chemicals (India) P1985 Phentolamine Mesylate 1G ₹4100 2022-05-26 Buy
TCI Chemicals (India) P1985 Phentolamine Mesylate 100MG ₹2700 2022-05-26 Buy

Properties

Melting point :180-182 °C(lit.)
Density :1.2256 (rough estimate)
refractive index :1.6320 (estimate)
storage temp. :2-8°C
solubility :ethanol: 26 mg/mL
form :powder
color :white to off-white
Water Solubility :50 mg/mL
Merck :14,7264
Stability :Aq. Solutions Cannot be Stored
InChI :InChI=1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4)
InChIKey :OGIYDFVHFQEFKQ-UHFFFAOYSA-N
SMILES :N(CC1=NCCN1)(C1C=CC(C)=CC=1)C1C=CC=C(O)C=1.S(=O)(=O)(O)C

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Phentolamine is a reversible antagonist of α-adrenergic receptors, non-specifically binding all α1- and α2-adrenoceptors with nanomolar affinities. When given intravenously, phentolamine rapidly and transiently increases local blood flow, which has proven useful for the management of hypertensive emergencies. Phentolamine also has applications in controlling chronic and emergent pain.

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