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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antiepileptic and anticonvulsant >Piperine

Piperine

Piperine Structure
  • ₹1890 - ₹140151.28
  • Product name: Piperine
  • CAS: 94-62-2
  • MF: C17H19NO3
  • MW: 285.34
  • EINECS:202-348-0
  • MDL Number:MFCD00005839
  • Synonyms:Piperine,98%;Piperidine, 1-(2E,4E)-5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl-;1-piperinoylpiperidine;PIPERINE(P);PIPERINE(RG);PIPERLINE;Piperine SynonyMs (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine;Piperine (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine
12 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)
  • ottokemi

Package

  • 50MG
  • 1G
  • 1gm
  • 5gm
  • 5G
  • 10G
  • 100G
  • 1KG
  • 1SAMPLE-K
  • ManufacturerSigma-Aldrich(India)
  • Product numberP49007
  • Product descriptionPiperine ≥97%
  • Packaging1G
  • Price₹1890
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP49007
  • Product descriptionPiperine ≥97%
  • Packaging5G
  • Price₹2510
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW290904
  • Product descriptionPiperine ≥95%, FG
  • Packaging1SAMPLE-K
  • Price₹5141.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number75047
  • Product descriptionPiperine analytical standard
  • Packaging50MG
  • Price₹7166.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2211
  • Product descriptionPiperine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging50MG
  • Price₹13520.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.21036
  • Product descriptionPiperine for synthesis
  • Packaging10G
  • Price₹13810
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW290904
  • Product descriptionPiperine ≥95%, FG
  • Packaging100G
  • Price₹24886.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberW290904
  • Product descriptionPiperine ≥95%, FG
  • Packaging1KG
  • Price₹140151.28
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP0460
  • Product descriptionPiperine
  • Packaging1G
  • Price₹2500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP0460
  • Product descriptionPiperine
  • Packaging5G
  • Price₹5900
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1528
  • Product descriptionPiperine, ≥97%
  • Packaging1gm
  • Price₹2493
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 1528
  • Product descriptionPiperine, ≥97%
  • Packaging5gm
  • Price₹5895
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) P49007 Piperine ≥97% 1G ₹1890 2022-06-14 Buy
Sigma-Aldrich(India) P49007 Piperine ≥97% 5G ₹2510 2022-06-14 Buy
Sigma-Aldrich(India) W290904 Piperine ≥95%, FG 1SAMPLE-K ₹5141.88 2022-06-14 Buy
Sigma-Aldrich(India) 75047 Piperine analytical standard 50MG ₹7166.15 2022-06-14 Buy
Sigma-Aldrich(India) PHR2211 Piperine Pharmaceutical Secondary Standard; Certified Reference Material 50MG ₹13520.43 2022-06-14 Buy
Sigma-Aldrich(India) 8.21036 Piperine for synthesis 10G ₹13810 2022-06-14 Buy
Sigma-Aldrich(India) W290904 Piperine ≥95%, FG 100G ₹24886.68 2022-06-14 Buy
Sigma-Aldrich(India) W290904 Piperine ≥95%, FG 1KG ₹140151.28 2022-06-14 Buy
TCI Chemicals (India) P0460 Piperine 1G ₹2500 2022-05-26 Buy
TCI Chemicals (India) P0460 Piperine 5G ₹5900 2022-05-26 Buy
ottokemi P 1528 Piperine, ≥97% 1gm ₹2493 2022-05-26 Buy
ottokemi P 1528 Piperine, ≥97% 5gm ₹5895 2022-05-26 Buy

Properties

Melting point :131-135 °C(lit.)
Boiling point :427.77°C (rough estimate)
Density :1.0864 (rough estimate)
refractive index :1.5400 (estimate)
FEMA :2909 | PIPERINE
storage temp. :Sealed in dry,Room Temperature
solubility :Slightly soluble in water, 10% soluble in alcohol, soluble only in certain oils
form :Crystalline Powder
pka :12.22(at 18℃)
color :Off-white to tan or yellow-tan
Odor :at 1.00 % in propylene glycol. pepper animal
Odor Type :spicy
Water Solubility :40 mg/L (18 ºC)
Merck :14,7472
JECFA Number :1600
BRN :90741
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :MXXWOMGUGJBKIW-YPCIICBESA-N
LogP :2.66
CAS DataBase Reference :94-62-2(CAS DataBase Reference)
NIST Chemistry Reference :Piperine(94-62-2)
EPA Substance Registry System :2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4E)- (94-62-2)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

Piperine is a natural alkaloid that can be isolated from black pepper. It activates transient receptor potential vanilloid type 1 receptor (TRPV1; EC50 = 38 μM) and modulates GABAA receptors (EC50s = 43-60 μM). At similar levels, piperine inhibits both monoamine oxidases (MAOs), with IC50 values of 21 and 7 μM for MAO-A and MAO-B, respectively. Like other natural compounds containing methylenedioxyphenyl substituents, piperine affects cytochrome P450 (CYP) isoforms, inhibiting CYP3A species (Ki ~ 5 μM) and increasing expression of CYP1A and CYP2B in liver. It also has a biphasic effect on P-glycoprotein activity.

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