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ChemicalBook > Product Catalogue >API >Antipyretic analgesics >Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) >Piroxicam

Piroxicam

Piroxicam Structure
  • ₹6051.18 - ₹40225.7
  • Product name: Piroxicam
  • CAS: 36322-90-4
  • MF: C15H13N3O4S
  • MW: 331.35
  • EINECS:252-974-3
  • MDL Number:MFCD00057317
  • Synonyms:4-HYDROXY-2-METHYL-3-(PYRID-2-YL-CARBAMOYL)-2H-1,2-BENZOTHIAZINE 1,2-DIOXIDE;4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE;4-hydroxy-2-methyl-n-2-pyridinyl-2h-1,2-benzothiazine-3-carboxamide 1,1-dioxide;3,4-DIHYDRO-2-METHYL-4-OXO-N-2-PYRIDYL-2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE;AURORA KA-6753;4-Hydroxy-2-Methyl-1,2-Benzothiazine-3-Carboxylic Acid Ethylester-1,1-Dioxide;Piroxicam, Feldene;PIROXICAM ASSAY STANDARD BP(CRM STANDARD)
8 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 200MG
  • 1G
  • 5G
  • 10G
  • ManufacturerTCI Chemicals (India)
  • Product numberP1905
  • Product descriptionPiroxicam
  • Packaging10G
  • Price₹21000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP5654
  • Product descriptionPiroxicam ≥98% (TLC)
  • Packaging1G
  • Price₹6051.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP0847
  • Product descriptionPiroxicam meets USP testing specifications
  • Packaging1G
  • Price₹6062
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1588
  • Product descriptionPiroxicam Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging200MG
  • Price₹13704.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP5654
  • Product descriptionPiroxicam ≥98% (TLC)
  • Packaging5G
  • Price₹21097.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP0847
  • Product descriptionPiroxicam meets USP testing specifications
  • Packaging5G
  • Price₹26586.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP5654
  • Product descriptionPiroxicam ≥98% (TLC)
  • Packaging10G
  • Price₹27289.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP0847
  • Product descriptionPiroxicam meets USP testing specifications
  • Packaging10G
  • Price₹40225.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P1905 Piroxicam 10G ₹21000 2022-05-26 Buy
Sigma-Aldrich(India) P5654 Piroxicam ≥98% (TLC) 1G ₹6051.18 2022-06-14 Buy
Sigma-Aldrich(India) P0847 Piroxicam meets USP testing specifications 1G ₹6062 2022-06-14 Buy
Sigma-Aldrich(India) PHR1588 Piroxicam Pharmaceutical Secondary Standard; Certified Reference Material 200MG ₹13704.45 2022-06-14 Buy
Sigma-Aldrich(India) P5654 Piroxicam ≥98% (TLC) 5G ₹21097.93 2022-06-14 Buy
Sigma-Aldrich(India) P0847 Piroxicam meets USP testing specifications 5G ₹26586.2 2022-06-14 Buy
Sigma-Aldrich(India) P5654 Piroxicam ≥98% (TLC) 10G ₹27289.83 2022-06-14 Buy
Sigma-Aldrich(India) P0847 Piroxicam meets USP testing specifications 10G ₹40225.7 2022-06-14 Buy

Properties

Melting point :198-200°C
Density :1.3664 (rough estimate)
refractive index :1.6320 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, soluble in methylene chloride, slightly soluble in anhydrous ethanol. It shows polymorphism (5.9).
form :Solid
pka :6.3 (2:1 dioxane-water)
color :White to Light yellow
Water Solubility :Soluble in water, ethanol, chloroform, ethyl acetate.
λmax :358nm(H2O)(lit.)
Merck :14,7506
BCS Class :2
InChIKey :QYSPLQLAKJAUJT-UHFFFAOYSA-N
CAS DataBase Reference :36322-90-4(CAS DataBase Reference)
NIST Chemistry Reference :Piroxicam(36322-90-4)
EPA Substance Registry System :2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide (36322-90-4)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P314 Get medical advice/attention if you feel unwell.
P405 Store locked up.

Description

Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) that non-selectively and reversibly inhibits both isoforms of cyclooxygenase (COX; IC50 = 1.57 and 1.69 μM for COX-1 and COX-2, respectively). It has an extended half-life of about 40 hours, which allows once daily administration leading to sustained plasma and tissue levels. In addition to its anti-inflammatory effects, piroxicam is known to be an effective analgesic that has been used extensively in the treatment of arthritis. It has also been used to inhibit COX activity for treatment of certain cancers in animals. As with other NSAIDs, the extended use of piroxicam results in damage to the gastrointestinal lining.

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