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ChemicalBook > Product Catalogue >API >Antipyretic analgesics >Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) >Meloxicam

Meloxicam

Meloxicam Structure
  • ₹4600 - ₹20250
  • Product name: Meloxicam
  • CAS: 71125-38-7
  • MF: C14H13N3O4S2
  • MW: 351.4
  • EINECS:615-253-8
  • MDL Number:MFCD00868752
  • Synonyms:MeloxicaM, BP;MeloxicaM API;4-Hydroxy-2-Methyl-N-(5-Methylthiazol-2-yl)-2H-benzo[e][1,2]thiazine-3-carboxaMide 1,1-dioxide;Meloxicam Solution, 100ppm;4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide;4-Hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxid;Coxicam;MOBEC
4 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 500MG
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberM1959
  • Product descriptionMeloxicam
  • Packaging5G
  • Price₹4600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM1959
  • Product descriptionMeloxicam
  • Packaging25G
  • Price₹13300
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1799
  • Product descriptionMeloxicam Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹16215.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number444800
  • Product descriptionMeloxicam - CAS 71125-38-7 - Calbiochem A cell-permeable, non-steroidal anti-inflammatory drug (NSAID) of the oxicam family which preferentially inhibits the inducible isoform of COX-2 (IC??
  • Packaging100MG
  • Price₹20250
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M1959 Meloxicam 5G ₹4600 2022-05-26 Buy
TCI Chemicals (India) M1959 Meloxicam 25G ₹13300 2022-05-26 Buy
Sigma-Aldrich(India) PHR1799 Meloxicam Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹16215.85 2022-06-14 Buy
Sigma-Aldrich(India) 444800 Meloxicam - CAS 71125-38-7 - Calbiochem A cell-permeable, non-steroidal anti-inflammatory drug (NSAID) of the oxicam family which preferentially inhibits the inducible isoform of COX-2 (IC?? 100MG ₹20250 2022-06-14 Buy

Properties

Melting point :255 °C
Density :1.613±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble
form :Off-white solid
pka :4.08 in water; 4.24 ± 0.01 in water/ethanol (1:1); 4.63 ± 0.03 in water/ethanol (1:4)
color :yellow
Water Solubility :practically insoluble in water(0.154 mg/mL), with higher solubility observed in strong acids and bases.
Merck :14,5826
BCS Class :2(CLogP), 4 (LogP)
Stability :Stable. Incompatible with strong oxidizing agents.
InChI :InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)
InChIKey :ZRVUJXDFFKFLMG-UHFFFAOYSA-N
SMILES :S1(=O)(=O)C2=CC=CC=C2C(O)=C(C(NC2=NC=C(C)S2)=O)N1C
EPA Substance Registry System :2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-, 1,1-dioxide (71125-38-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Known as a nonsteroidal anti-inflammatory drug (NSAID), Meloxicam is commonly used to treat pain or inflammation caused by rheumatoid arthritis and osteoarthritis in adults. It is also used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is effective to reduce pain, inflammation, swelling, and stiffness of the joints. Developed by Boehringer-Ingelheim, Meloxicam is a derivative of oxicam that can relieve the symptoms of arthritis, primary dysmenorrhea, fever with analgesic and antipyretic properties. Meloxicam was approved for use in April 2000.
Anti-inflammatory effects of meloxicam function by inhibiting the prostaglandin synthetase (cyclooxygenase 1 and 2) which results in a decrease of the synthesis of prostaglandins. As prostaglandins are chemicals that contribute to inflammation especially within joints, which leads to the common symptoms of pain, tenderness, and swelling associated with arthritis, inhibition of their synthesis can be associated with the analgesic and antipyretic effects of meloxicam. As a result, inflammation and its accompanying symptoms are reduced. Meloxicam starts to relieve pain about 30 to 60 minutes after administration.

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