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Potassium canrenoate

Potassium canrenoate Structure
  • ₹0
  • Product name: Potassium canrenoate
  • CAS: 2181-04-6
  • MF: C11H15KO2
  • MW: 218.33
  • EINECS:218-554-9
  • MDL Number:MFCD00058500
  • Synonyms:CANRENOIC ACID POTASSIUM SALT;canrenoic acid potassium;4,6-ANDROSTADIEN-17ALPHA-YL-PROPIONIC ACID-17BETA-OL-3-ONE POTASSIUM SALT;17-HYDROXY-3-OXOPREGNA-4,6-DIENE-21-CARBOXYLIC ACID;17-HYDROXY-3-OXOPREGNA-4,6-DIENE-21-CARBOXYLIC ACID POTASSIUM SALT;POTASSIUM CANRENOATE;Canrenone, potassium salt;Canrenoate
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :242-244°C (dec.)
Density :1.345 g/cm3
storage temp. :Refrigerator
solubility :Methanol (Slightly)
form :powder
color :light yellow to tan
CAS DataBase Reference :2181-04-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.

Description

Potassium canrenoate is a competitive aldosterone antagonist. It has been shown to counteract the effects of aldosterone-induced blood pressure increases in animals with high sodium intake. Potassium canrenoate is clinically used for its anti-fibrotic effects and has been shown to reduce cardiovascular fibrosis in animal models. At higher concentrations, however, potassium canrenoate has been found to produce genotoxic effects to the liver and an increase in tumor incidence studies with rodents.

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