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ChemicalBook > Product Catalogue >Biochemical Engineering >Nucleoside drugs >Nucleotides and their analogs >Potassium orotate

Potassium orotate

Potassium orotate Structure
  • ₹6960.48
  • Product name: Potassium orotate
  • CAS: 24598-73-0
  • MF: C5H3KN2O4
  • MW: 194.19
  • EINECS:246-341-0
  • MDL Number:MFCD00039118
  • Synonyms:Potassium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate;OROTIC ACID MONOPOTASSIUM SALT;OROTIC ACID POTASSIUM SALT;POTASSIUM OROTATE;1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicacimonopotassiumsal ;1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicacimonopotassiumsalt ;ba2658 ;dioron
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Brand

  • Sigma-Aldrich(India)

Package

  • 100G
  • ManufacturerSigma-Aldrich(India)
  • Product numberO2875
  • Product descriptionOrotic acid potassium salt ≥98%
  • Packaging100G
  • Price₹6960.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) O2875 Orotic acid potassium salt ≥98% 100G ₹6960.48 2022-06-14 Buy

Properties

Melting point :>300°C
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Aqueous Base (Slightly)
form :Solid
color :White to Light Yellow
Stability :Hygroscopic
LogP :-0.928 (est)
CAS DataBase Reference :24598-73-0(CAS DataBase Reference)
EPA Substance Registry System :4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, monopotassium salt (24598-73-0)

Safety Information

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Description

Orotic acid (OA) is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) orSaccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.

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