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ChemicalBook > Product Catalogue >API >Vitamins and Minerals medicines >Vitamin B drugs >Orotic acid

Orotic acid

Orotic acid Structure
  • ₹3052.65 - ₹27697
  • Product name: Orotic acid
  • CAS: 65-86-1
  • MF: C5H4N2O4
  • MW: 156.1
  • EINECS:200-619-8
  • MDL Number:MFCD00006027
  • Synonyms:2,6-Dihydroxy-4-pyrimidinecarboxylic acid;4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-;4-pyrimidinecarboxylicacid,1,2,3,6-tetrahydro-2,6-dioxo-[qr] ;6-carboxyuracil[qr] ;acideorotique(french)[qr] ;acidoorotico[qr] ;acidumoroticum(latin)[qr] ;ai3-25478[qr]
3 prices
Selected condition:

Brand

  • ALFA India
  • Sigma-Aldrich(India)

Package

  • 10G
  • 100g
  • 500g
  • ManufacturerALFA India
  • Product numberALF-B25349-22
  • Product descriptionOrotic acid, anhydrous, 97%
  • Packaging100g
  • Price₹7197
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-B25349-36
  • Product descriptionOrotic acid, anhydrous, 97%
  • Packaging500g
  • Price₹27697
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO2750
  • Product descriptionOrotic acid ≥98% (titration), anhydrous
  • Packaging10G
  • Price₹3052.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-B25349-22 Orotic acid, anhydrous, 97% 100g ₹7197 2022-05-26 Buy
ALFA India ALF-B25349-36 Orotic acid, anhydrous, 97% 500g ₹27697 2022-05-26 Buy
Sigma-Aldrich(India) O2750 Orotic acid ≥98% (titration), anhydrous 10G ₹3052.65 2022-06-14 Buy

Properties

Melting point :≥300 °C
Boiling point :280.29°C (rough estimate)
Density :1.6814 (rough estimate)
refractive index :1.4800 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO : 32 mg/mL (205.00 mM; Need ultrasonic and warming)
form :Crystalline Powder
pka :pK1:1.8(+1);pK2:9.55(0) (25°C)
color :White
Water Solubility :Slightly soluble
Merck :13,6942
BRN :383901
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :PXQPEWDEAKTCGB-UHFFFAOYSA-N
LogP :-0.830
CAS DataBase Reference :65-86-1(CAS DataBase Reference)
NIST Chemistry Reference :Orotic acid(65-86-1)
EPA Substance Registry System :Orotic acid (65-86-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Orotic acid is a nutritional medicine, also known as vitamin B13, but doesn’t belong to vitamins and is a kind of white and shiny needle-shaped crystal or crystalline powder obtained from water. It is odorless with sour taste. It has a melting point of 345~346 ℃. It is insoluble in water, ethanol and organic solvents, slightly soluble in hot water but insoluble in ether. Its reaction with hydrogen peroxide and concentrated hydrochloric acid can generate 5-chlorouracil-4-carboxylic acid. It can be obtained through the following processes: first: diethyl oxalate and ethyl acetate can have condensation reaction for synthesis of diethyl ketobutyric acid; use urea for cyclization reaction to obtain the 5-ethoxycarbonyl-methylene hydantoin followed by hydrolysis, ring expansion reaction and acid precipitation to get the finished product. In the field of medicine, it can be used for making drugs for liver protection for the treatment of jaundice and common liver dysfunction disease.

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