Pyocyanine
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- ₹10254.3 - ₹49437.78
- Product name: Pyocyanine
- CAS: 85-66-5
- MF: C13H10N2O
- MW: 210.23
- EINECS:
- MDL Number:MFCD01794662
- Synonyms:Pyocyanine;1-Oxylato-5-methylphenazin-5-ium;5-Methyl-1(5H)-phenazinone;Sanasin;Sanazin;Pyocyanin, Ready Made Solution from Pseudomonas aeruginosa;pyocyanin;5-methylphenazin-1-one
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 500μL
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberP0046
- Product descriptionPyocyanin from Pseudomonas aeruginosa, ≥98% (HPLC)
- Packaging25MG
- Price₹49437.78
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP0046
- Product descriptionPyocyanin from Pseudomonas aeruginosa, ≥98% (HPLC)
- Packaging5MG
- Price₹12697.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberR9532
- Product descriptionPyocyanin, Ready Made Solution from Pseudomonas aeruginosa 5?mg/mL in DMSO
- Packaging500μL
- Price₹10254.3
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P0046 | Pyocyanin from Pseudomonas aeruginosa, ≥98% (HPLC) | 25MG | ₹49437.78 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P0046 | Pyocyanin from Pseudomonas aeruginosa, ≥98% (HPLC) | 5MG | ₹12697.73 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R9532 | Pyocyanin, Ready Made Solution from Pseudomonas aeruginosa 5?mg/mL in DMSO | 500μL | ₹10254.3 | 2022-06-14 | Buy |
Properties
Melting point :133°
Boiling point :349.76°C (rough estimate)
Density :1.1427 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
form :solid
pka :2.42±0.20(Predicted)
color :Dark blue
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
Boiling point :349.76°C (rough estimate)
Density :1.1427 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
form :solid
pka :2.42±0.20(Predicted)
color :Dark blue
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
Safety Information
Symbol(GHS): |
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Signal word: | Warning | |||||||||||||||||||||
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Description
P. aeruginosa is a common pathogen affecting immunocompromised patients with acute diseases such as pneumonia and vasculitis or chronic diseases such as cystic fibrosis. It produces several phenazine toxic metabolites, in which the most predominant is a blue pigment, pyocyanin. Pyocyanin has been shown to accelerate neutrophil apoptosis in vitro, resulting in resolution of acute inflammation, that is beneficial for bacterial survival. It also induces a 10-fold acceleration of neutrophil apoptosis in vitro. Pyocyanin production results in reduced bacterial clearance from the lungs of immunocompromised patients. It has also been reported to induce apoptosis in human lung epithelial cells and to induce premature cellular senescence in mammalian cells. Pyocyanin undergoes nonenzymatic reduction by NADPH, which produces hydrogen peroxide and depletes intracellular glutathione levels, causing oxidative stress in susceptible cells.More related product prices
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