Rauwolscine hydrochloride
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- Product name: Rauwolscine hydrochloride
- CAS: 6211-32-1
- MF: C21H27ClN2O3
- MW: 390.9
- EINECS:228-279-6
- MDL Number:MFCD00069342
- Synonyms:RAUWOLSCINE HYDROCHLORIDE (A-YOHIMBINE) A2 AD;α-Yohimbine hydrochloride, 17α-Hydroxy-20α-yohimban-16 β-carboxylic acid methyl ester hydrochloride;YohiMban-16-carboxylicacid, 17-hydroxy-, Methyl ester, hydrochloride (1:1), (16b,17a,20a)-;YOHIMBINE HCL, ALPHA-;20-alpha-yohimban-16-beta-carboxylicacid,17-alpha-hydroxy-,methylester,hyd ;alpha-yohimbinhydrochloride ;RAUWOLFSCINE HYDROCHLORIDE;RAUWOLSCINE HYDROCHLORIDE
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Properties
Melting point :270-280°C
storage temp. :Store at RT
solubility :H2O: soluble
form :solid
color :white
Sensitive :Light Sensitive
storage temp. :Store at RT
solubility :H2O: soluble
form :solid
color :white
Sensitive :Light Sensitive
Safety Information
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Description
Rauwolscine is a natural alkaloid that acts as a selective and reversible α2-adrenergic receptor antagonist (Ki = 12 nM). It is a stereoisomer of yohimbine, which potently antagonizes both α1- and α2-adrenergic receptors. Rauwolscine also acts as a receptor antagonist at the serotonin 5-HT2B receptor (Ki = 14.3 nM) and as a weak partial agonist at 5-HT1A (IC50 = 1.3 μM). The α2-adrenergic receptor has diverse physiological functions and antagonists like rauwolscine have numerous applications, including the modulation of mood and behavior.Related product price
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