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REVERSIN 121

REVERSIN 121 Structure
  • ₹49730.05
  • Product name: REVERSIN 121
  • CAS: 174630-04-7
  • MF: C34H47N3O9
  • MW: 641.75
  • EINECS:
  • MDL Number:MFCD03788012
  • Synonyms:REVERSIN 121;BOC-ASP(OBZL)-LYS(Z)-OTBU;L-Lysine, N-[(1,1-dimethylethoxy)carbonyl]-L-α-aspartyl-N6-[(phenylmethoxy)carbonyl]-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester
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Brand

  • Sigma-Aldrich(India)

Package

  • 3MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberR1276
  • Product descriptionReversin 121 ≥97% (HPLC), powder
  • Packaging3MG
  • Price₹49730.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) R1276 Reversin 121 ≥97% (HPLC), powder 3MG ₹49730.05 2022-06-14 Buy

Properties

Boiling point :786.8±60.0 °C(Predicted)
Density :1.163±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO or ethanol: soluble
form :powder
pka :10.75±0.46(Predicted)
color :white

Safety Information

Symbol(GHS):
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a Kd value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma membrane vesicles from multidrug-resistant cells, and reconstituted proteoliposomes as well as in a variety of MDR1-expressing intact tumor cells.