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RO 15-4513

RO 15-4513 Structure
  • ₹53886.85 - ₹214248.4
  • Product name: RO 15-4513
  • CAS: 91917-65-6
  • MF: C15H14N6O3
  • MW: 326.32
  • EINECS:
  • MDL Number:MFCD00078598
  • Synonyms:RO 15-4513;8-AZIDO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID ETHYL ESTER;ETHYL 8-AZIDO-6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]-[1,4]BENZODIAZEPINE-3-CARBOXYLATE;4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-azido-5,6-dihydro-6-oxo-, ethyl ester;8-Azido-5,6-dihydro-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester;Azidomazenil;Ethyl 8-azido-6-dihyro-5-methyl-6-oxo-4H-imidazo[1,5-A][1,4]benzodiazepine-3-carboxylic acid ethyl ester;4H-Imidazo(1,5-A)(1,4)benzodiazepine-3-carboxylic acid, 8-azido-5,6-dihydro-5-methyl-6-oxo-, ethyl ester
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 25MG
  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberR109
  • Product descriptionRo 15-4513 solid
  • Packaging100MG
  • Price₹214248.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR109
  • Product descriptionRo 15-4513 solid
  • Packaging25MG
  • Price₹53886.85
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) R109 Ro 15-4513 solid 100MG ₹214248.4 2022-06-14 Buy
Sigma-Aldrich(India) R109 Ro 15-4513 solid 25MG ₹53886.85 2022-06-14 Buy

Properties

storage temp. :Desiccate at +4°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.8 mg/mL
form :solid
color :tan
CAS DataBase Reference :91917-65-6

Safety Information

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Signal word:
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Description

RO 15-4513 is a high affinity benzodiazepine ligand which acts as a partial inverse agonist at recombinant diazepam-sensitive (DS) benzodiazepine α1-, α2-, α3- and α5-GABAA receptors. It has also been shown to activate GABAA R α4 and GABAA R α6. In addition, RO 15-4513 acts as a partial agonist at diazepam-insensitive (DI) benzodiazepine receptors. Furthermore, studies show that ethanol can inhibit the binding of RO 15-4513 to α4/6β3δ GABAA receptors. RO 15-4513 has a similar structure to flumazenil, which differs by an azido group at the C7 position of the imidazo-benzodiazepine ring.

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