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ROQUEFORTINE C

ROQUEFORTINE C Structure
  • ₹54958.53
  • Product name: ROQUEFORTINE C
  • CAS: 58735-64-1
  • MF: C22H23N5O2
  • MW: 389.45
  • EINECS:
  • MDL Number:MFCD00133802
  • Synonyms:10b-(1,1-dimethyl-2-propenyl)-6,10b,11,11a-tetrahydro-3-(1H-imidazol-4-ylmethylene)-2H-pyrazino(1,2:1,5)pyrrolo(2,3-b)indole-1,4(3H,5aH)-dione, Isoroquefortine C, Roquefortin, Roquefortine C;(3E,5aS,5aβ)-10bβ-(1,1-Dimethyl-2-propenyl)-3-(1H-imidazol-4-yl)methylene-6,10b,11,11aα-tetrahydro-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione;(5aS)-3-[(E)-(1H-Imidazole-4-yl)methylene]-10bβ-(1,1-dimethyl-2-propenyl)-1,3,4,5aβ,6,10b,11,11aα-octahydro-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione;2H-Pyrazino[1',2':1,5]pyrrolo[2,3-B]indole-1,4(3H,5ah)-dione, 10B-(1,1-dimethyl-2-propenyl)-6,10B,11,11A-tetrahydro-3-(1H-imidazol-4-ylmethylene)-, (3Z)-;Aids031208;Aids-031208;Nsc292134;2H-Pyrazino[1′,2′:1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione, 10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(1H-imidazol-5-ylmethylene)-,(3E,5aS,10bR,11aS)-
Price1 Properties Safety Information Description
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Brand

  • Sigma-Aldrich(India)

Package

  • 500μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0406
  • Product descriptionRoquefortine C ≥98% (HPLC), from Penicillium roqueforti
  • Packaging500μG
  • Price₹54958.53
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0406 Roquefortine C ≥98% (HPLC), from Penicillium roqueforti 500μG ₹54958.53 2022-06-14 Buy

Properties

Melting point :202-205℃
Boiling point :768.3±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :chloroform: soluble1mg/mL
form :White to off-white solid.
pka :11.10±0.40(Predicted)
color :White to off-white
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Roquefortine C is a mycotoxin that was first isolated from a strain of P. roqueforti, a species of Penicillium commercially used to ripen blue-veined cheeses. It has also been isolated from other members of the Penicillium genus found in contaminated food products where it displays neurotoxic properties. It has been shown to both activate a P-glycoprotein transport system involved in the efflux of xenobiotics and to inhibit cytochrome P450 3A detoxification enzymes. It has also been used as a biomarker for penitrem A intoxication.

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