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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Neuronal Signaling >5-HT Receptor agonists >Rizatriptan benzoate

Rizatriptan benzoate

Rizatriptan benzoate  Structure
  • ₹5700 - ₹30299.18
  • Product name: Rizatriptan benzoate
  • CAS: 145202-66-0
  • MF: C22H25N5O2
  • MW: 391.48
  • EINECS:604-465-6
  • MDL Number:MFCD00866224
  • Synonyms:RIZATRIPTAN BENZOATE;N,N-DIMETHYL-5-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1H-INDOLE-3-ETHANAMINE, BENZOATE;n,n-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1h-indol-3-yl]ethylamine benzoate;Rizatrimptan Benzoate;Rizatrimptan;Rizatriptan monobenzoate;N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-;Acid Bixente triptans
4 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 250MG
  • 500MG
  • ManufacturerTCI Chemicals (India)
  • Product numberR0181
  • Product descriptionRizatriptan Benzoate
  • Packaging50MG
  • Price₹5700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberR0181
  • Product descriptionRizatriptan Benzoate
  • Packaging250MG
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0247
  • Product descriptionRizatriptan benzoate salt ≥98% (HPLC)
  • Packaging10MG
  • Price₹10835.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1889
  • Product descriptionRizatriptan Benzoate Pharmaceutical Secondary Standards; Certified Reference Material
  • Packaging500MG
  • Price₹30299.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) R0181 Rizatriptan Benzoate 50MG ₹5700 2022-05-26 Buy
TCI Chemicals (India) R0181 Rizatriptan Benzoate 250MG ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) SML0247 Rizatriptan benzoate salt ≥98% (HPLC) 10MG ₹10835.83 2022-06-14 Buy
Sigma-Aldrich(India) PHR1889 Rizatriptan Benzoate Pharmaceutical Secondary Standards; Certified Reference Material 500MG ₹30299.18 2022-06-14 Buy

Properties

Melting point :178-180°C
storage temp. :2-8°C
solubility :H2O: ≥5mg/mL
form :powder
color :white to beige
Merck :14,8241
InChIKey :JPRXYLQNJJVCMZ-UHFFFAOYSA-N
CAS DataBase Reference :145202-66-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Known as a 5-hydroxytryptamine agonist, Rizatriptan Benzoate is the benzoate salt form of rizatriptan with anti-migraine activity, which can be used to treat the migraine headaches. It is FDA-approved to use in the treatment of acute migraine attacks with or without aura, especially taken at the first sign of a migraine headache. However, it cannot prevent future migraine attacks and it is ineffective to prevent other types of headache.
The pain of migraine headaches is believed to be induced by dilated blood vessels inside the head. Rizatriptan Benzoate relieves the pain by inducing vasoconstriction, which functions as an agonist at serotonin 5-HT1B and 5-HT1D receptors. The selective receptor binding is effective to constrict cranial vessels and inhibit the transmission of nociception, thus providing relief of migraine headaches.

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