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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Endocrinology & Hormones >Estrogen / progestogen Receptor agonists >(S)-Equol

(S)-Equol

(S)-Equol Structure
  • ₹0
  • Product name: (S)-Equol
  • CAS: 531-95-3
  • MF: C15H14O3
  • MW: 242.27
  • EINECS:208-522-2
  • MDL Number:MFCD00200962
  • Synonyms:(S)-3,4-DYHYDRO-3-(4-HYDROXYPHENYL)-2H-1-BENZOPYRAN-7-OL;(S)-4',7-DIHYDROXYISOFLAVANCE;R,S-EQUOL;4',7-ISOFLAVANDIOL;4',7-DIHYDROXYISOFLAVAN;7,4'-ISOFLAVANDIOL;(S)-3,4-dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol;(S)-EQUOL
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :189-190°C
alpha :D -21.5°
Boiling point :312.25°C (rough estimate)
Density :1.1914 (rough estimate)
refractive index :1.5557 (estimate)
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO (Soluble), Ethanol (Slightly), Methanol (Slightly)
form :Solid
pka :9.94±0.40(Predicted)
color :White to Pale Yellow
CAS DataBase Reference :531-95-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-Equol is a non-steroidal estrogen. The estrogen receptor (ER) agonist activity of the naturally occurring (S)-enantiomer (EC50 = 85 and 65 nM for human ERα and ERβ, respectively) is similar to that of genistein but exceeds that of daidzein. (S)-Equol preferentially binds ERβ (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki = 6.41 nM). Also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies.

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