Safinamide
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- ₹14200
- Product name: Safinamide
- CAS: 133865-89-1
- MF: C17H19FN2O2
- MW: 302.34
- EINECS:603-772-2
- MDL Number:MFCD00897036
- Synonyms:SAFINAMIDE:(S)-(+)-2-[4-(3-FLUOROBENZYLOXY)BENZYLAMINO]PROPANAMIDE METHANSULFONATE;FCE 26743;Safinamide;EMD 1195686;FCE 26743;EMD-1195686;EMD1195686;FCE-26743;Safinamide ,Safinamide base;Safinamide Intermediate 2;(S)-(+)-2-[4-(3-Fluorobenzyloxy)benzylamino]propanamice methansulfonate;CS-484
1 prices
Selected condition：
Brand
- TCI Chemicals (India)
Package
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberS0935
- Product descriptionSafinamide
- Packaging100MG
- Price₹14200
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | S0935 | Safinamide | 100MG | ₹14200 | 2022-05-26 | Buy |
Properties
Melting point :208-212°
Boiling point :476.7±40.0 °C(Predicted)
Density :1.189±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO (up to 50 mg/ml).
form :solid
pka :16.03±0.50(Predicted)
color :White
Merck :14,8315
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Boiling point :476.7±40.0 °C(Predicted)
Density :1.189±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO (up to 50 mg/ml).
form :solid
pka :16.03±0.50(Predicted)
color :White
Merck :14,8315
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Safinamide (133865-89-1) is a selective and reversible inhibitor of monoamine oxidase B (MAO-B, IC50=98 nM with greater than 100-fold selectivity over MAO-A.1?Displays anticonvulsant activity2?and protects against kainate-induced seizures and hippocampal neurodegeneration in rat models3. Reduces overactive glutamatergic signaling via use-dependent sodium channel blockade.4?A novel therapeutic for Parkinson’s disease with multiple modes of action.5?Effective as an add-on to dopamine agonist therapy in early Parkinson’s.6Related product price
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