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ChemicalBook > Product Catalogue >API >Nervous system drugs >Cholinergic drugs >Scopolamine hydrobromide

Scopolamine hydrobromide

Scopolamine hydrobromide Structure
  • ₹12940
  • Product name: Scopolamine hydrobromide
  • CAS: 114-49-8
  • MF: C17H21NO4.BrH
  • MW: 384.26
  • EINECS:204-050-6
  • MDL Number:MFCD00012647
  • Synonyms:02,4]non-7-ylester,hydrobromide,[7(s)-(1alpha,2beta,4beta,5alpha,7beta) ;hyoscyinehydrobromide ;hysco ;isoscopil ;Benzeneacetic acid, a-(hydroxyMethyl)-, (1a,2b,4b,5a,7b)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-ylester, hydrobroMide (1:1), (aS)-;ScopolaMine-d3 HBr 3H2O;Hyosol;Tranaxine
Price1 Properties Safety Information Description
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Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product number5.05818
  • Product descriptionScopolamine Hydrobromide - CAS 114-49-8 - Calbiochem
  • Packaging1G
  • Price₹12940
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 5.05818 Scopolamine Hydrobromide - CAS 114-49-8 - Calbiochem 1G ₹12940 2022-06-14 Buy

Properties

Melting point :195-199 °C (dry matter)(lit.)
alpha :D25 -24 to -26° (c = 5, calculated on anhydrous basis)
storage temp. :Store at RT
solubility :H2O: 50 mg/mL
form :powder
color :white to off-white
InChI :InChI=1/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/s3
InChIKey :WTGQALLALWYDJH-MLRWSLNSNA-N
SMILES :[C@]12([H])O[C@@]1([H])[C@@]1([H])N(C)[C@]2([H])C[C@@H](OC(=O)[C@H](CO)C2C=CC=CC=2)C1.Br |&1:0,3,5,9,12,16,r|
CAS DataBase Reference :114-49-8(CAS DataBase Reference)
EPA Substance Registry System :Scopolamine hydrobromide (114-49-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

(-)-Scopolamine hydrobromide is the hydrobromide salt of the anticholinergic natural product Scopolamine, isolated from plants of the Solanaceae family. Scopolamine exhibits anticholinergic properties through competitive inhibition of acetylcholine muscarinic receptors with selectivity for mAChR M1. Suppression of the cholinergic response results in decreased activity of the parasympathetic nervous system, widely exploited in studies concerning parasympathetic functioning.

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Suppliers and manufacturers

Ralington Pharma Prism Industries Ltd Pharma Affiliates ALKALOIDS CORP ALCHEM INTERNATIONAL PRIVATE LTD VITAL LABORATORIES PVT LTD Alkaloids Corporation CLEARSYNTH LABS LTD. A.J Chemicals Pharmaffiliates Analytics and Synthetics P. Ltd