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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antifungal Drugs >Sertaconazole nitrate

Sertaconazole nitrate

Sertaconazole nitrate Structure
  • ₹4232.58 - ₹17320
  • Product name: Sertaconazole nitrate
  • CAS: 99592-39-9
  • MF: C20H15Cl3N2OS.HNO3
  • MW: 500.78
  • EINECS:
  • MDL Number:MFCD00918063
  • Synonyms:NITRATE SERTACONAZOLE;1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole mononitrate;1-[2-[(7-Chlorobenzo[b]thien-3-yl)Methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-iMidazole Nitrate;DerMovit;Ertaczo;Sertaconazole Mononitrate;1H-Imidazole, 1-[2-[(7-chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1);SEROTONIN
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0888
  • Product descriptionSertaconazole nitrate ≥98% (HPLC)
  • Packaging10MG
  • Price₹4232.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0888
  • Product descriptionSertaconazole nitrate ≥98% (HPLC)
  • Packaging50MG
  • Price₹17320
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0888 Sertaconazole nitrate ≥98% (HPLC) 10MG ₹4232.58 2022-06-14 Buy
Sigma-Aldrich(India) SML0888 Sertaconazole nitrate ≥98% (HPLC) 50MG ₹17320 2022-06-14 Buy

Properties

Melting point :158-160°
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :pKb: 7.26(at 25℃)
color :white to beige
InChIKey :HAAITRDZHUANGT-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Sertaconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Sertaconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.

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