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Shikalkin

Shikalkin Structure
  • ₹41135 - ₹138083.7
  • Product name: Shikalkin
  • CAS: 54952-43-1
  • MF: C16H16O5
  • MW: 288.3
  • EINECS:
  • MDL Number:MFCD00016668
  • Synonyms:5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione;SHIKALKIN;1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)- (9ci);Arnebin-4;Nsc 291845;shiconin;Shikonin (mixture of optical isomers, about 1:1);1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-penten-1-yl)-
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberS7576
  • Product descriptionShikonin ≥98% (HPLC)
  • Packaging10MG
  • Price₹41135
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS7576
  • Product descriptionShikonin ≥98% (HPLC)
  • Packaging50MG
  • Price₹138083.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) S7576 Shikonin ≥98% (HPLC) 10MG ₹41135 2022-06-14 Buy
Sigma-Aldrich(India) S7576 Shikonin ≥98% (HPLC) 50MG ₹138083.7 2022-06-14 Buy

Properties

Melting point :144-145 °C
Boiling point :567.4±50.0 °C(Predicted)
Density :1.373±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :methanol: soluble1mg/mL
pka :7.34±0.20(Predicted)
form :powder or solid
color :red to brown
LogP :4.350 (est)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.

Description

Shikonin has been used:
  • to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
  • as an inhibitor of renal aerobic glycosis and a potential
  • as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
  • to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death


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