TACRINE HYDROCHLORIDE
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- Product name: TACRINE HYDROCHLORIDE
- CAS: 1684-40-8
- MF: C13H15ClN2
- MW: 234.72
- EINECS:216-867-5
- MDL Number:MFCD00012657
- Synonyms:1,2,3,4-tetrahydro-9-acridinaminmonohydrochloride ;1,2,3,4-tetrahydro-9-aminoacridinehydrochloride ;1,2,3,4-tetrahydro-9-amino-acridinmonohydrochloride ;9-amino-1,2,3,4-tetrahydro-acridinhydrochloride ;tacrine monohydrochloride;1,2,3,4-TETRAHYDRO-9-ACRYDINAMINEHCLMONOHYDRATE;1,2,3,4-TETRAHYDRO-9-ACRIDINAMINEHYDROCHLORIDEMONOHYDRATE;1,2,3,4-Tetrahydro-9-Acridinamine Hydrochloride Dihydrate
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Properties
Melting point :280-284 °C(lit.)
storage temp. :Inert atmosphere,2-8°C
solubility :Soluble in aqueous buffers
pka :pKa 9.8 (Uncertain)
form :Crystalline solid
color :White to light yellow
CAS DataBase Reference :1684-40-8(CAS DataBase Reference)
EPA Substance Registry System :Tacrine hydrochloride (1684-40-8)
storage temp. :Inert atmosphere,2-8°C
solubility :Soluble in aqueous buffers
pka :pKa 9.8 (Uncertain)
form :Crystalline solid
color :White to light yellow
CAS DataBase Reference :1684-40-8(CAS DataBase Reference)
EPA Substance Registry System :Tacrine hydrochloride (1684-40-8)
Safety Information
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Description
Tacrine is a derivative of aminoacridine which functions as an inhibitor of both AChE and butyrylcholinesterase. It has been used clinically in the treatment of Alzheimer’s disease. Tacrine also inhibits the uptake of serotonin and noradrenaline in rat cerebral cortex and decreases depolarization-induced calcium influx through L-type calcium channels in SN56 neuronal cells.Related product price
- EC 3.1.1.8
₹43123.5-172183.2