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ChemicalBook > Product Catalogue >Biochemical Engineering >Protein Research >Protease inhibitors >TLCK

TLCK

TLCK Structure
  • ₹12156.48 - ₹86069.58
  • Product name: TLCK
  • CAS: 4272-74-6
  • MF: C14H22Cl2N2O3S
  • MW: 369.31
  • EINECS:224-266-4
  • MDL Number:MFCD00065395
  • Synonyms:N-ALPHA-TOSYL-LYS CHLOROMETHYL KETONE, HYDROCHLORIDE;NALPHA-P-TOSYL-L-LYSIN CHLOROMETYL KETONE;N-ALPHA-P-TOSYL-L-LYSIN CHLOROMETYL KETONE HCL;N-ALPHA-P-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE;P-TOLUENESULFONYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE;N-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE;N-TOSYL-LYS-CHLOROMETHYLKETONE;TOS-LYS-CHLOROMETHYLKETONE HCL
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Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • 500MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7254
  • Product descriptionNα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥96% (TLC), powder
  • Packaging100MG
  • Price₹12156.48
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number90182
  • Product descriptionNα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥99.0% (AT)
  • Packaging100MG
  • Price₹12870.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7254
  • Product descriptionNα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥96% (TLC), powder
  • Packaging500MG
  • Price₹42715.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number90182
  • Product descriptionNα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥99.0% (AT)
  • Packaging500MG
  • Price₹50693.48
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7254
  • Product descriptionNα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥96% (TLC), powder
  • Packaging1G
  • Price₹86069.58
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) T7254 Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥96% (TLC), powder 100MG ₹12156.48 2022-06-14 Buy
Sigma-Aldrich(India) 90182 Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥99.0% (AT) 100MG ₹12870.93 2022-06-14 Buy
Sigma-Aldrich(India) T7254 Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥96% (TLC), powder 500MG ₹42715.45 2022-06-14 Buy
Sigma-Aldrich(India) 90182 Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥99.0% (AT) 500MG ₹50693.48 2022-06-14 Buy
Sigma-Aldrich(India) T7254 Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥96% (TLC), powder 1G ₹86069.58 2022-06-14 Buy

Properties

Melting point :~165 °C (dec.)
storage temp. :-20°C
solubility :H2O: 50 mg/mL
form :powder
color :white to pink
optical activity :[α]20/D 7.8±0.5°, c = 2% in H2O
BRN :7106867
CAS DataBase Reference :4272-74-6

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tosyllysine chloromethylketone (TLCK) is an active site-directed agent that inhibits serine proteinases with trypsin-like activity. TLCK may also act non-selectively with thiol groups and thereby inhibit cysteine proteinases and other enzymes. To prevent proteolytic degradation, TLCK may be used in protein purification protocols. TLCK selectively inactiviates clostripain obtained from C. histolyticum.

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