TYROTHRICIN
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- Product name: TYROTHRICIN
- CAS: 1404-88-2
- MF: C6H13NO5
- MW: 179.17112
- EINECS:215-771-0
- MDL Number:MFCD33021606
- Synonyms:bactratycin ;coltirot ;duboscrudecrystals ;hydrotricine ;3-[(3R,6S,9S,12S,15S,17S,20S,22R,25S,28S)-20-(2-amino-2-oxoethyl)-9-(3-aminopropyl)-15-[(4-hydroxyphenyl)methyl]-6-(2-methylpropyl)-2,5,8,11,14,18,21,24,27-nonaoxo-3,22,25-tris(phenylmethyl)-12-propan-2-yl-1,4,7,10,13,16,19,23,26-nonazabicyclo[26.3.0]hentriacontan-17-yl]propanoic acid;3-[(3R,6S,9S,12S,15S,17S,20S,22R,25S,28S)-20-(2-azanyl-2-oxo-ethyl)-9-(3-azanylpropyl)-15-[(4-hydroxyphenyl)methyl]-6-(2-methylpropyl)-2,5,8,11,14,18,21,24,27-nonaoxo-3,22,25-tris(phenylmethyl)-12-propan-2-yl-1,4,7,10,13,16,19,23,26-nonazabicyclo[26.3.0]hentriacontan-17-yl]propanoic acid;intradermtyrothricin ;martricin
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Properties
storage temp. :Store at -20°C
solubility :Practically insoluble in water, soluble in ethanol (96 per cent) and in methanol.
form :Solid
color :White to off-white
EPA Substance Registry System :Tyrothricin (1404-88-2)
solubility :Practically insoluble in water, soluble in ethanol (96 per cent) and in methanol.
form :Solid
color :White to off-white
EPA Substance Registry System :Tyrothricin (1404-88-2)
Safety Information
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Description
Tyrothricin is a complex of two unrelated peptide families, gramicidin complex and tyrocidines complex, produced by Bacillus brevis and discovered by Dubos in 1939. Typically, tyrothricin is composed of 20% of the linear pentadecylpeptide gramicidins and 80% of cyclic decapeptide tyrocidines. Both the gramicidins and tyrocidines act by disrupting bacterial cell wall integrity, but by differing mechanisms. Tyrothricin is used clinically for bacterial skin infections in some countries.Related product price
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