Tacalcitol
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- ₹0
- Product name: Tacalcitol
- CAS: 57333-96-7
- MF: C27H44O3
- MW: 416.64
- EINECS:
- MDL Number:
- Synonyms:(1α，3β-5Z，7E，24R)-9，10-Secoholesta-5，7，10(19)-triene-1，3，24-triol;lα，24-Dihydroxycholecalciferol;lα，24R-Dihy-droxyvitamin D3;[5Z,7E,24R,(+)]-9,10-Secocholesta-5,7,10(19)-triene-1α,3β,24-triol;1α,24(R)-Dihydroxyvitamin D3;1α,24R-Dihydroxyvitamin D3;(1a,3b,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol;C12919
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Properties
Boiling point :565.0±50.0 °C(Predicted)
Density :1.06
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :20mg/mL in DMSO, 20mg/mL in DMF, 20mg/mL in Ethanol
pka :14.43±0.40(Predicted)
form :Powder
color :White to off-white
CAS DataBase Reference :57333-96-7(CAS DataBase Reference)
Density :1.06
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :20mg/mL in DMSO, 20mg/mL in DMF, 20mg/mL in Ethanol
pka :14.43±0.40(Predicted)
form :Powder
color :White to off-white
CAS DataBase Reference :57333-96-7(CAS DataBase Reference)
Safety Information
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Description
Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity. In addition, the active form of vitamin D, 1,25-dihydroxy vitamin D3, decreases the proliferation and increases differentiation of keratinocytes. 1,24-dihydroxy Vitamin D3 is an analog of 1,25-dihydroxy vitamin D3 which, when used in a 4 μg/g ointment, safely and effectively suppresses psoriasis. It also is effective at increasing the time interval between phototherapy cycles when ultraviolet light is used for psoriasis. 1,24-dihydroxy Vitamin D3 inhibits the growth of both normal and psoriatic human keratinocytes (IC50 ~ 10 nM) via the vitamin D receptor. It also suppresses the production of RANTES and IL-8 by human dermal fibroblasts and reduces cutaneous lymphocyte-associated antigen on CD4+ T cells, impairing migration and skin infiltration.Related product price
- VITAMIN D3
₹22602.6
