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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Immunosuppressants >Tacrolimus Monohydrate

Tacrolimus Monohydrate

Tacrolimus Monohydrate Structure
  • ₹10200 - ₹48160.43
  • Product name: Tacrolimus Monohydrate
  • CAS: 109581-93-3
  • MF: C44H71NO13
  • MW: 822.05
  • EINECS:617-559-7
  • MDL Number:MFCD11045918
  • Synonyms:15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;TACROLIMUS HYDRATE/TSUKUBAENOLIDE HYDRATE;(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone;Tacrolimus (150 mg);(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-Methoxycyclohexyl]-1-Methylethenyl]-14,16-diMethoxy-4,10,12,18-tetraMethyl-8-(2-propen-1-yl)-;FK-506 monohydrate, >=98%;Tacrolimus /FK506 monohydrate;,8s*,9e,12r*,14r*,15s*,16r*,18s*,19s*,26ar*))-
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)

Package

  • 5MG
  • 10MG
  • 50MG
  • 150MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberF4679
  • Product descriptionFK-506 monohydrate ≥98% (HPLC)
  • Packaging5MG
  • Price₹29270.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1809
  • Product descriptionTacrolimus Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging150MG
  • Price₹48160.43
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM2258
  • Product descriptionTacrolimus Monohydrate
  • Packaging50MG
  • Price₹22900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM2258
  • Product descriptionTacrolimus Monohydrate
  • Packaging10MG
  • Price₹10200
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) F4679 FK-506 monohydrate ≥98% (HPLC) 5MG ₹29270.8 2022-06-14 Buy
Sigma-Aldrich(India) PHR1809 Tacrolimus Pharmaceutical Secondary Standard; Certified Reference Material 150MG ₹48160.43 2022-06-14 Buy
TCI Chemicals (India) M2258 Tacrolimus Monohydrate 50MG ₹22900 2022-05-26 Buy
TCI Chemicals (India) M2258 Tacrolimus Monohydrate 10MG ₹10200 2022-05-26 Buy

Properties

Melting point :127-129°
alpha :D23 -84.4° (c = 1.02 in chloroform)
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL
form :powder
color :White to Almost white
Merck :14,9025
InChIKey :NWJQLQGQZSIBAF-MLAUYUEBSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

FK-506 monohydrate is a potent immunosuppressant, neuroprotective and neuroregenerative, as well as an in vitro T cell proliferation blocker. This compound disrupts calcineurin-mediated signal transduction in T lymphocytes and interacts with its FK-506-binding protein-12 (FKBP12).

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Suppliers and manufacturers

Viruj Pharmaceuticals Pvt Ltd Fishfa Biogenics Concord Biotech Limited Molsyns Research BIOCON LIMITED CONCORD BIOTECH LIMITED CLEARSYNTH LABS LTD. TCI Chemicals (India) Pvt. Ltd. SynZeal Research Pvt Ltd Pharmaffiliates Analytics and Synthetics P. Ltd