Tacrolimus
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- ₹11730 - ₹23487.8
- Product name: Tacrolimus
- CAS: 104987-11-3
- MF: C44H69NO12
- MW: 804.02
- EINECS:1308068-626-2
- MDL Number:MFCD00869853
- Synonyms:(2-propenyl)-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*,8s*,9e,12r*,14r*,15s*,16r*,18s* ;,19s*,26ar*))- ;16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1 ;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;L 679934;FK-506:FR-900506;Fujimycin Prozraf;Tacrolimus,micronisedandpharmagrade
3 prices
Selected condition:
Brand
- Sigma-Aldrich
- Sigma-Aldrich(India)
Package
- 5MG
- 1ML
- ManufacturerSigma-Aldrich
- Product number342500
- Product descriptionFK-506, Streptomyces sp. - CAS 104987-11-3 - Calbiochem Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2.
- Packaging5MG
- Price₹11730
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number342500
- Product descriptionFK-506, Streptomyces sp. - CAS 104987-11-3 - Calbiochem Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2.
- Packaging5MG
- Price₹11730
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT-049
- Product descriptionTacrolimus solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1ML
- Price₹23487.8
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich | 342500 | FK-506, Streptomyces sp. - CAS 104987-11-3 - Calbiochem Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. | 5MG | ₹11730 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 342500 | FK-506, Streptomyces sp. - CAS 104987-11-3 - Calbiochem Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. | 5MG | ₹11730 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | T-049 | Tacrolimus solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? | 1ML | ₹23487.8 | 2022-06-14 | Buy |
Properties
Melting point :113-115°C
Boiling point :871.7±75.0 °C(Predicted)
Density :1.19±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: >3 mg/mL
form :solid
pka :9.97±0.70(Predicted)
color :white
Water Solubility :Freely soluble in DMSO or ethanol. Poorly soluble in water.Soluble in dimethyl sulfoxide, ethanol, water, acetone, chloroform, ethyl acetate, ether, methanol and dimethyl formamide.
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :QJJXYPPXXYFBGM-LFZNUXCKSA-N
CAS DataBase Reference :104987-11-3(CAS DataBase Reference)
Boiling point :871.7±75.0 °C(Predicted)
Density :1.19±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: >3 mg/mL
form :solid
pka :9.97±0.70(Predicted)
color :white
Water Solubility :Freely soluble in DMSO or ethanol. Poorly soluble in water.Soluble in dimethyl sulfoxide, ethanol, water, acetone, chloroform, ethyl acetate, ether, methanol and dimethyl formamide.
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :QJJXYPPXXYFBGM-LFZNUXCKSA-N
CAS DataBase Reference :104987-11-3(CAS DataBase Reference)
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
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Description
Interacts with the immunophilins cyclophilin and FKBP-12.Tacrolimus is used as an immunosuppressive drug that blocks T cell proliferation in vitro. It is also used in the treatment of other T cell-mediated diseases such as eczema, Kimura's disease and Cushing's syndrome. Further, it is used as a research tool in chemically induced dimerization applications. In addition, it is used in liver transplantation and to suppress the inflammation in ulcerative cells. In dermatology, it is used as an ointment to treat eczema especially atopic dermatitis.More related product prices
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